Prostate Specific Antigen as a Predictive Factor for Androgenemia in Women

April 2022 in “ Indian Journal of Forensic Medicine & Toxicology ”

Ali M. M. Al-Bahadly, Maytham Khazza Kadhim AL-Behadili, Mohammed Shakir Atiyah

Prostate Specific Antigen hyperandrogenism testosterone dehydroepiandrosterone sulfate sex hormone-binding globulin PSA DHEA-S SHBG

TLDR PSA can help diagnose high androgen levels in women.

The study investigated the potential of using Prostate Specific Antigen (PSA) as a diagnostic marker for hyperandrogenic conditions in women by examining 105 girls aged 17-26. It was found that PSA concentration in peripheral blood increases with higher levels of testosterone (T) and dehydroepiandrosterone sulfate (DHEA-S), and decreases with lower levels of sex hormone-binding globulin (SHBG). The results suggest that PSA is a valuable marker for diagnosing hyperandrogenism in women, demonstrating a clear relationship between androgen levels and PSA concentration.

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