TLDR PSA can help diagnose high androgen levels in women.
The study investigated the potential of using Prostate Specific Antigen (PSA) as a diagnostic marker for hyperandrogenic conditions in women by examining 105 girls aged 17-26. It was found that PSA concentration in peripheral blood increases with higher levels of testosterone (T) and dehydroepiandrosterone sulfate (DHEA-S), and decreases with lower levels of sex hormone-binding globulin (SHBG). The results suggest that PSA is a valuable marker for diagnosing hyperandrogenism in women, demonstrating a clear relationship between androgen levels and PSA concentration.
58 citations,
November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
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82 citations,
May 2016 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
16 citations,
January 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.
19 citations,
July 2013 in “The obstetrician & gynaecologist” The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
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56 citations,
October 1983 in “Archives of Dermatology” Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.
