Disruptors of Androgen Action and Synthesis

    January 2015 in “ Elsevier eBooks ”
    J. Thomas Sanderson
    Studysummary This review discusses the potential antiandrogenic effects of environmental chemicals on reproductive development, highlighting concerns about their impacts on humans but reports no new clinical findings.
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    Research cited in this study 3

    1. The Antiandrogen Cyproterone Acetate: Discovery, Chemistry, Basic Pharmacology, Clinical Use and Tool in Basic Research Experimental and Clinical Endocrinology & Diabetes · 2009
    2. Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2004
    3. A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride Clinical Pharmacology & Therapeutics · 1998