research Steroid Hormones: Overview and Medical Applications
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
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research Testosterone and Doping Control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research Clinical Characterization of Men with Long QT Syndrome and Torsades de Pointes Associated with Hypogonadism: A Review and Pharmacovigilance Study
Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.
research New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice
Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
research Minoxidil Increases 17β-Hydroxysteroid Dehydrogenase and 5α-Reductase Activity in Cultured Human Dermal Papilla Cells from Balding Scalp
Minoxidil boosts enzymes that help hair growth.
research Low Anabolic Profile in Assessing a Patient’s Overall Hair Loss
Some supplements and hormones can increase hair loss by raising DHT levels.
research Androgens Affect the Activity of Human Sebocytes in Culture Depending on the Localization of the Sebaceous Glands, and Their Effect Is Antagonized by Spironolactone
Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.
research Gender Differences in Skin Aging and the Changing Profile of the Sex Hormones with Age
The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Pharmacology of Anabolic Steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach
Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
research Lack of Effect of Spironolactone on Hair Shaft Diameter in Hirsute Females
Spironolactone did not make hair thinner in women with excess hair growth.
research Testosterone, 17 Ks, 17 Beta E2 FSH-LH Variations and Hirsutism Modifications During Spironolactone Therapy
Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.
research Effect of Lifestyle Modifications on Reproductive Function Among Infertile Obese Women with Polycystic Ovarian Syndrome
Lifestyle changes improve reproductive function and hormonal balance in obese women with PCOS.
research Effect of High Levels of Testosterone on Cardiovascular Risk in Polycystic Ovary Syndrome
High testosterone increases heart disease risk in women with PCOS.
research Clinical, Metabolic, and Endocrine Parameters in Response to Metformin and Lifestyle Intervention in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, and Placebo-Controlled Trial
Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.
research Pharmacodynamic Modeling of Finasteride, a 5 Alpha-Reductase Inhibitor
Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.
research Hormonal Regulation and Systemic Signals of Skin Aging
Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
research Genetic Analysis of Androgen Receptors in Development and Disease
The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.
research Clinical Approaches to PCOS: A Survey of the NASPAG Membership
Doctors vary in how they initially test for PCOS, but most agree on using oral contraceptives and lifestyle changes as first treatments.
research Chapter 1: Facial Feminization Surgery: A Global Approach
The document recommends a multidisciplinary approach and experience sharing to advance facial feminization surgery as a medical field.
research Endocrinological Assessment in Transgender Individuals
The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.
research Androgen Binding Profiles of Two Distinct Nuclear Androgen Receptors in Atlantic Croaker (Micropogonias Undulatus)
Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.
research Polycystic Ovary Syndrome and Other Androgen Excess-Related Conditions: Can Changes in Dietary Intake Make a Difference?
Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.
research The Contribution of Endogenous and Exogenous Factors to Male Alopecia
Genetic and environmental factors, like smoking and exercise, affect male hair loss.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
research Pattern of Dermatologic Manifestations in Polycystic Ovarian Disease Cases from a Tertiary Care Hospital
The most common skin problems in polycystic ovarian disease are hirsutism and acne, and managing these symptoms is key for treatment.
research Potential Role of Cinnamon (Cinnamomum Verum) to Reduce the Risk of Polycystic Ovary Syndrome by Managing Obesity: A Review
Cinnamon may help manage obesity and improve conditions related to Polycystic Ovary Syndrome (PCOS).
research The Princeton III Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease
The Princeton III Consensus recommends assessing cardiovascular risk in men with erectile dysfunction and prioritizing heart health before treating ED, especially in those with potential heart disease.
research A Prospective Observational Study of Polycystic Ovarian Syndrome Among Adolescent and Young Girls at Tertiary Care Hospital
The study found that 7.21% of young girls have polycystic ovarian syndrome, with symptoms like irregular periods, abnormal hair growth, and acne. Early diagnosis is important to prevent long-term complications.