Low Anabolic Profile in Assessing a Patient’s Overall Hair Loss

    January 2015 in “ Hair therapy & transplantation
    Lawrence J. Shapiro
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    TLDR Some supplements and hormones can increase hair loss by raising DHT levels.
    The 2015 document examines the relationship between supplements, hormones, and hair loss. It finds that whey protein isolate (WPI), growth hormones (GH), and anabolic precursors can contribute to hair loss by increasing levels of dihydrotestosterone (DHT). Anabolic steroids, known for muscle building, also cause hair loss by converting to DHT. The study notes that branched-chain amino acids (BCAAs) in WPI can raise testosterone levels, affecting hair growth. Other supplements like human chorionic gonadotropin (HCG), dehydroepiandrosterone (DHEA), and androstenedione are discussed for their impact on hair loss, with DHEA notably increasing levels of testosterone, androstenedione, and DHT, particularly in women. GH and IGF-1 are shown to lower sex hormone-binding globulin (SHBG) levels, thus increasing androgens and potentially leading to hair loss. The document suggests that medical practitioners should consider patients' supplement intake when planning hair loss prevention strategies. It reports that over 800 patients have seen accelerated hair regrowth by following a Low Anabolic Profile and using Enhanced Whey Protein with low BCAAs after hair transplants. However, the document also states that there is no evidence that bio-identical low doses of GH promote hair growth and that GH can actually lead to hair loss by increasing serum IGF-1 levels. Creatine is mentioned as a supplement that can raise DHT levels, potentially causing hair loss. The document emphasizes the importance of healthcare professionals being aware of the effects of supplements on hair loss and suggests avoiding anabolic products to mitigate future hair loss. The number of participants in the referenced studies was not provided.
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