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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Understanding hair follicle anatomy helps diagnose hair disorders.

Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Apoptosis is crucial for healthy skin and treating skin diseases.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Autophagy is important for human hair growth and health.

The document suggests medicine should integrate biological and cultural factors and focus on holistic, equitable care.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

The study concluded that scalp tumors show different patterns based on age, gender, and tumor thickness, and emphasized the importance of early detection and scalp examinations.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Topical 0.1% tacrolimus significantly improved ear infections in cats.

Type I interferons play a key role in the development of various skin diseases.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.