Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that tenofovir alafenamide fumarate (TAF) is an effective and safer alternative to tenofovir disoproxil fumarate (TDF) for chronic hepatitis B, with fewer long-term side effects like nephrotoxicity and decreased bone density.

This report describes six cases of hair loss in African American women after switching to tenofovir alafenamide, suggesting it as a possible adverse effect in this population.

This study found that dermatoses are common in people living with HIV and may serve as indicators of disease stage, with certain conditions more prevalent when CD4+ counts are below 200/mm³.

This study introduces three spectrophotometric techniques for accurately determining finasteride and tadalafil in their combined pharmaceutical form, demonstrating their sustainability, sensitivity, and suitability for quality assurance, alongside a dissolution study following FDA guidelines.

In this study, researchers developed a coamorphous form of tadalafil and finasteride, showing improved solubility and dissolution in vitro, with results successfully translated in vivo in rats. They reported reasonable stability, suggesting this form could serve as a therapeutic alternative to the current marketed combination.

In this study, researchers created a coamorphous system combining tadalafil and finasteride that demonstrated improved solubility, dissolution, and stability compared to their physical mixture, offering potential therapeutic advantages for benign prostatic hyperplasia.

This study observed that exposure to heavy metal salts affected skin and hair morphology in mice, with lead acetate decreasing keratinocyte proliferation and zinc sulfate and sodium dichromate increasing it.

This case study describes a patient with secondary syphilis, including alopecia syphilitica diffusa, whose symptoms resolved completely after treatment with benzylpenicillin following prednisolone prophylaxis.

In this laboratory study on mice, researchers found that both platelet-rich plasma and salmon DNA serum promoted wound healing, with platelet-rich plasma providing faster results due to its bioactive growth factors.

The researchers reported that freeze-dried collagen-activated platelet-rich plasma increased transforming growth factor-β1 levels compared to non freeze-dried PRP with collagen, suggesting a potential benefit for tissue regeneration.

This study found that among Indian women with PCOS, coping skills did not significantly impact psychiatric morbidity, quality of life, or body-mass index.

In these initial clinical studies, NAP monotherapy showed significant reductions in HBsAg levels among patients with chronic HBV, suggesting potential as part of future combination therapies.

This review of stem cell-based tissue engineering treatments in preclinical burn wound models reports promising improvements in skin repair, suggesting potential as an enhanced therapy for burn wounds.

This study found that finasteride treatment reduced caspase-1 expression, suggesting that androgens may influence immune processes in the hair cycle of androgenetic alopecia.

In this study, intradermal injections of QR678 were found to significantly reduce hair fall in men with androgenetic alopecia over 6 months, with superior improvements in hair density and thickness compared to PRP.

This study found that gene-regulatory interactions among parental alleles contribute significantly to heterosis in early stages of maize development, with many differentially expressed genes showing non-additive expression in hybrids.

In this study, QR678® and QR678 Neo® injections significantly improved hair density and thickness in women with PCOS-related alopecia over eight sessions, with effects lasting over a year.

This study found that L-glutamine supplementation in Hanwoo steers under heat stress did not affect growth performance or muscle and adipose tissue gene expression but was associated with increased immune cells and reduced HSP90 expression.

This study found that the repressive histone mark H2AK119ub links inhibitory FGF signals with the quiescent state in hair follicle stem cells, revealing a signaling-epigenetic axis crucial for maintaining stem cell quiescence and tissue homeostasis.

In this article, the authors describe a successfully treated case of a newborn with ichthyosis using a neonatal protocol involving an incubator with controlled temperature and humidity, sepsis prevention, eye protection, and emollient care without keratolytics during the early neonatal period.

This study discusses how polynucleotide-based cosmetic products can improve aging skin in patients with particular morphotypes by restoring cellular metabolism, enhancing microcirculation, and promoting intracellular matrix remodeling, offering potential benefits for reversing chrono- and photo-aging and aiding tissue recovery after cosmetic or surgical procedures.

This study highlights the underexplored allergenic potential of Trichophyton rubrum, a dermatophyte, which can trigger IgE-mediated allergic reactions and a Th2 immune response shift, underscoring the need for its inclusion in diagnostic panels and further research for treating chronic mycoses and related allergies.

This study conducted among sex workers in Kostanay reported a low HIV prevalence of 0.8% but a high syphilis rate of 15.6%, highlighting significant social risks and emphasizing the need to expand pre-exposure prophylaxis and prevention programs.

In this report, the author summarized activities from a six-month internship in community and hospital pharmacy settings, exploring topics like skin microbiome health implications and advancements in antiviral therapy for Hepatitis B and D, highlighting the pharmacist's role in patient care and innovative treatments.

This review outlines the strategies for managing TB-IRIS in HIV patients, emphasizing early detection, prevention, and appropriate treatment to reduce morbidity and mortality.

In this study, a very low-calorie ketogenic diet significantly improved metabolic and hormonal profiles in obese men, but did not significantly enhance most semen parameters except for sperm motility.

This study investigated the possible role of neutrophil extracellular traps in contributing to fibrosis in stenotic Crohn's disease.

This clinical study found that Rosmarinum officinalis mother tincture significantly improved hair volume and density in individuals with diffuse hair loss by enhancing hair parameters measured through a hair shedding visual scale and ponytail thickness test.

This study observed that using moringa leaf extract in hair tonic reduced hair loss among the sampled students, with the average hair loss decreasing from 118.75 strands to 79.25 strands per day.

This study examined hairline patterns among the Etche people in Rivers State, Nigeria, and found straight-lined hairlines to be the most common, observed in 34.4% of participants, with significant differences in hairline dimensions by gender and marital status, but not by religious affiliation.