January 2024 in “Journal of lipid research” In this study, finasteride was found to reduce cholesterol levels and delay atherosclerosis in LDL receptor-deficient mice, and men using finasteride reported lower cholesterol levels, suggesting potential cardiovascular benefits by improving lipid profiles.
June 2023 in “Frontiers in Genetics” This study suggests that the curly hair phenotype in Mangalitza pigs may involve complex gene interactions related to calcium signaling and lipid metabolism, rather than changes in TRPM2 or CYP4F3 expression.
November 2023 in “ACS Omega” This study reported that a novel cationic liposome formulation for delivering encapsulated Cas9 protein and sgRNA successfully decreased SRD5α2 mRNA expression by 29.7% in vitro, suggesting a potential alternative treatment option for conditions like prostate cancer and benign prostatic hyperplasia without current drug side effects.
August 2025 in “Anais Brasileiros de Dermatologia” This review details phenol's dermatological uses and underscores its potent skin rejuvenation effects but emphasizes the need for caution due to risks of serious complications, including cardiac arrhythmias and organ failure, particularly with improper use or large-area applications.
September 2024 in “Journal of the American Academy of Dermatology” Subcision is the most efficient, cost-effective, and safest treatment for post-acne boxcar scarring in skin of color.
July 2023 in “GLOBAL JOURNAL FOR RESEARCH ANALYSIS” This study explored a new treatment approach using 20% TCA application with topical bimatoprost solution for managing alopecia areata of the eyebrows in cases where traditional treatments failed, offering a potential additional option for difficult cases.
119 citations
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May 1987 in “The Journal of Dermatologic Surgery and Oncology” This study found that pigmentation following sclerotherapy is likely caused by hemosiderin deposition from red blood cells rather than post-inflammatory hyperpigmentation, with most cases resolving spontaneously within 6–24 months.
36 citations
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December 2016 in “Dermatologic Therapy” In this study, TCA peel was found to be the most effective treatment for stable non-segmental vitiligo among the modalities tested, and it increased both MMP-9 and IL-17 tissue levels.
34 citations
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June 2005 in “Journal of cosmetic dermatology” This review discusses the effectiveness and potential complications of medium-depth and deep chemical peels for improving skin appearance and reports no clinical results; it highlights the need for careful procedure application.
31 citations
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February 1999 in “Dermatologic surgery” This report describes a case where solar-induced postinflammatory hyperpigmentation following laser hair removal was treated with a combination of topical treatments and serial TCA peels, resulting in only slight improvement.
25 citations
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November 1994 in “The Journal of Dermatologic Surgery and Oncology” In this study, acetone was not superior to other degreasers for enhancing the efficacy of trichloroacetic acid peels, and its higher flammability suggests using alternative degreasers to reduce workplace hazards.
7 citations
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January 1998 This article reviews various cosmetic procedures like botulinum A exotoxin and chemical peels for aesthetic enhancement but reports no new clinical findings, emphasizing existing methods.
4 citations
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July 1992 in “Clinics in Dermatology” Skin surgery has significantly advanced since 1950, with improvements in chemical peels, hair restoration, lasers, and Mohs surgery, and the development of less invasive techniques and specialized training.
2 citations
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March 2024 in “Dermatologic Surgery” The chemical peel improved the appearance of hand spots safely and effectively.
1 citations
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August 2024 in “Journal of Cutaneous and Aesthetic Surgery” In this study, 65% TCA showed better improvement for acne scars compared to 50% GA, but GA may be a safer alternative with fewer adverse effects.
1 citations
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July 2023 in “Pharmaceutics” In this study, researchers developed grooved microneedles made from hyaluronic acid for precise transdermal drug delivery, achieving accurate dosage with a high probability of delivery (98% or more) by using an easy-to-operate applicator for shearing force.
1 citations
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July 2011 in “The Egyptian Journal of Anatomy” This study observed that both TCA (35%) and GA (70%) chemical peels improved skin morphology and stimulated bulge stem cells in albino rats, with no significant difference between the two agents.
1 citations
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January 1994 in “The Journal of Dermatologic Surgery and Oncology” This article has no abstract and provides no new results; it is likely a narrative or commentary on chemical peels.
March 2026 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” In this study, patients with resistant alopecia areata treated with 35% trichloroacetic acid showed significantly better outcomes compared to those receiving superficial cryotherapy, with TCA demonstrating "excellent" results in 37.5% of cases versus 6.25% for cryotherapy.
July 2025 in “Journal of the Pakistan Medical Association” In this study, intralesional triamcinolone acetonide combined with 5-fluorouracil was more effective for treating keloids, showing a good to excellent response in 95% of cases and fewer side effects, compared to triamcinolone acetonide alone, which achieved a 70% response rate.
February 2025 in “Journal of Neonatal Surgery” This study reports that non-surgical treatments like triamcinolone acetonide and Botulinum toxin Type A reduced keloid volume by up to 80% in children, with combination therapies being safer and having fewer side effects.
October 2024 in “Journal of the Endocrine Society” This case study reported a 40-year-old woman developing Cushing Syndrome months after a single intraarticular injection of Triamcinolone Acetonide, highlighting the potential long-term effects of corticosteroid exposure and the importance of awareness about these risks for clinicians and patients.
December 2018 in “Dermatologic Surgery” This article outlines the comprehensive content of the Dermatologic Surgery journal, which covers a wide range of topics related to cosmetic and reconstructive skin surgery, including skin cancer, but presents no new clinical results.
January 2010 in “USFEU Scientific Library (Ural State Forest Engineering University)” This study developed a grooved microneedle platform enabling precise transdermal delivery of triamcinolone acetonide for alopecia areata, achieving accurate dosing by controlling groove position and drug concentration.
October 2021 in “The Egyptian Journal of Hospital Medicine ” This study concluded that combination therapies often yield better results for treating atrophic post-acne scars than single treatments.
February 2019 in “International journal of research in dermatology” This study found that a combination therapy of subcision, micro-needling, and TCA CROSS led to significant improvement in atrophic acne scars, with many patients showing improved scar grades over the treatment period.
19 citations
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June 1999 in “Steroids” This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.
25 citations
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November 2012 in “Thermochimica Acta” This study found that lipid extraction increased water diffusion in wool and hair fibers; the effect was more pronounced in hair, indicating lipids are crucial for water permeability.
9 citations
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August 2012 in “Thermochimica Acta” In this study, researchers found that finasteride exhibits a solid-solid phase relationship that is enantiotropic at normal pressure and becomes monotropic at higher pressure.
March 2026 in “Drug Testing and Analysis” This study observed that the degradation product PTeCA significantly increased in hair treated with oxidative cosmetics, suggesting it could be a reliable marker for detecting such treatments, with a proposed PTCA cut-off value using PTeCA as the gold standard.