research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
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research Audiological Abnormalities in Patients with Alopecia Areata
People with alopecia areata may be more likely to have a certain type of hearing loss.
research Perspectives in Dermatopathology: Telomeres and Telomerase in Aging and Cancer with Emphasis on Cutaneous Disease
Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
research Alopecia: The Search for Novel Agents Continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Ectopic Odorant Receptors Responding to Flavor Compounds in Skin Health and Disease: Current Insights and Future Perspectives
Skin odorant receptors respond to flavors and could be targeted to improve skin health and treat diseases.
research Integrin Beta 1 Establishes Liver Microstructure and Modulates Transforming Growth Factor Beta During Liver Development and Regeneration
Integrin β1 is crucial for liver structure and function, preventing fibrosis.
research Dicer- and Bulge Stem Cell-Dependent MicroRNAs During Induced Anagen Hair Follicle Development
MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.
research Novel Anti-Aging Gene NM_026333 Contributes to Proton-Induced Aging via NCX1 Pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
research Effects of Porcine Acellular Dermal Matrix Treatment on Wound Healing and Scar Formation: Role of Jag1 Expression in Epidermal Stem Cells
Porcine acellular dermal matrix treatment helps wounds heal faster and reduces scarring by affecting Jag1 in skin stem cells.
research Emerging Role of ILK and ELMO2 in the Integration of Adhesion and Migration Pathways
ILK and ELMO2 help cells move and stick together, important for wound healing and hair growth.
research New Potential Antiscarring Approaches
New antiscarring strategies show promise, including drugs, stem cells, and improved surgical techniques.
research Vascular Mechanisms in Laser Hair Removal
Laser hair removal might also work by damaging blood vessels around hair follicles.
research Inflammatory Perifollicular Fibrosis And Alopecia
Inflammation around hair follicles leads to hair loss, and treatments should focus on reducing this inflammation and other factors for effectiveness.
research Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin
PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
research Fibroblast Heterogeneity and Tertiary Lymphoid Tissues in the Kidney
Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
research From Structural Resilience to Cell Specification: Intermediate Filaments as Regulators of Cell Fate
Intermediate filaments are crucial for cell differentiation and stem cell function.
research The Inflammatory Aspect of Male and Female Pattern Hair Loss
Inflammation affects hair loss; anti-inflammatory treatments may help.
research The E6/E7 Oncogenes of Human Papillomavirus and Estradiol Regulate Hedgehog Signaling Activity in a Murine Model of Cervical Cancer
HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
research The Therapeutic Promise of Apoptosis
Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.
research Laser-Assisted Drug Delivery for the Treatment of Androgenetic Alopecia: Ablative Laser Fractional Photothermolysis to Enhance Cutaneous Topical Delivery of Platelet-Rich Plasma — With or Without Concurrent Bimatoprost and/or Minoxidil
Laser-assisted delivery of PRP, with or without bimatoprost and minoxidil, can effectively stimulate hair growth.
research Therapeutic Potential of Endogenous Stem Cells and Cellular Factors for Scar-Free Skin Regeneration
Using skin stem cells and certain molecules might lead to scar-free skin healing.
research The Increasing Importance of the Hair Follicle Route in Dermal and Transdermal Drug Delivery
Using hair follicles can improve skin drug delivery.
research Lateral Oblique Forehead Lines: Redefining Sleeping Lines and Treatment with Botulinum Toxin A
Lateral oblique forehead lines are caused by muscle movement, not sleep positions, and can be treated with botulinum toxin A.
research Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2
Certain genetic changes in the LSS gene cause a rare skin and hair condition.
research New Insight Into the Pathophysiology of Hair Loss Trigger a Paradigm Shift in the Treatment Approach
New research suggests treating hair loss should focus on common inflammation rather than individual molecules.
research MAD2B Acts as a Negative Regulatory Partner of TCF4 on Proliferation in Human Dermal Papilla Cells
MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.
research Mineralocorticoid Receptor Antagonists: A New Sprinkle of Salt and Youth
MR antagonists may improve skin health and wound healing, especially in aging.
research Metabolism and Skin Diseases
Skin health and diseases are closely linked to metabolic processes.
research Norepinephrine Regulates Keratinocyte Proliferation to Promote the Growth of Hair Follicles
Norepinephrine helps skin cells grow, which is important for hair growth.
research Acute Diffuse and Total Alopecia of the Female Scalp Associated with Borrelia Infection
A woman's total hair loss was linked to a Borrelia infection and was reversed with appropriate treatment.