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In this study, incorporating cetirizine into transferosome formulations significantly enhanced hair growth in mice and boosted IGF-1 and VEGF levels, suggesting that this method could be a promising alternative to traditional hair growth treatments, though further studies are needed to confirm its safety and suitability.

A new microneedle system may improve hair loss treatment by delivering ketoconazole directly to hair follicles.

This expert consensus statement highlights that while targeted cancer therapies significantly improve patient survival, they often result in various skin toxicities, underscoring the need for early diagnosis, management, and multidisciplinary care to maintain patients' quality of life and ensure treatment continuity.

This study developed a method using UHPLC-MS/MS and MSPE to detect trace amounts of sex hormones in cosmetics, finding progestins and estrogens in some products, and performed a preliminary safety evaluation for residual progesterone in hair loss prevention cosmetics.

This study found that in patients with AIDS-related non-Hodgkin lymphoma undergoing targeted therapy, a positive serum albumin change rate was significantly associated with better treatment outcomes, suggesting the value of dynamic albumin monitoring and nutritional support during treatment.

In this review, summarized findings suggest that emerging targeted immunotherapies may offer promising treatment options for alopecia areata by addressing the breakdown of hair follicle immune privilege.

In this study, researchers demonstrated that self-assembled gold nanoclusters with aptamers effectively deliver anti-NFκB aptamer drugs to inhibit hair follicle regeneration while being non-toxic to normal cells, offering a targeted treatment for hypertrichosis.

In this study, researchers used a 3D in vitro organ culture system to show that rifampicin-loaded lipid nanocapsules can penetrate hair follicles more effectively than free rifampicin, highlighting the potential advantage of nanocarrier-based antibiotic treatments for follicular infections.

Targeted immunological therapies offer safer and more effective treatments for skin conditions like eczema and psoriasis.

Targeted immunotherapy could be a promising new treatment for hair regrowth.

This article reviews the cutaneous side effects of immune checkpoint inhibitors and targeted therapies for skin cancers, noting that while generally mild, these effects can influence treatment decisions and quality of life, underscoring the need for physicians to be aware of these adverse reactions.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

This study demonstrated that a light-activated RNAi approach using hollow gold nanoshells effectively targets human prostate cancer cells with reduced off-target toxicity and material use compared to standard methods.

Men with androgenetic alopecia have unique metabolomic patterns that could help develop targeted treatments.

This study found that treating mtDNA mutator mice with the antioxidant SkQ1 delayed aging traits and extended their lifespan, potentially by alleviating mitochondrial dysfunction caused by reactive oxygen species.

This review summarizes existing studies on sorafenib, noting its promising effects in some cancers, but also highlights its limitations and potential synergy when combined with other anticancer treatments.

In this study, ectoderm-targeted transgenic mice with glucocorticoid receptor overexpression exhibited multiple epithelial defects, suggesting the role of NF-kappaB and p63 dysfunction in ectodermal dysplasia syndromes.

This study reported that targeted anticancer therapies are associated with an increased risk of alopecia compared to placebo, although the risk was lower compared to chemotherapy.

This study reports that a new DART-HRMS method can effectively analyze intact hair for drug use timelines, with cocaine detection aligning with forensic standards and identifying multiple drugs from high-resolution data.

This study observed that iontophoresis significantly improved the delivery of minoxidil sulfate to hair follicles compared to passive methods, suggesting potential benefits for alopecia treatment.

This study suggests that targeting specific immune pathways, such as IL-12/23 and Th2 cytokines, may offer new treatment options for alopecia areata, a T-cell-mediated disease without current mechanism-specific therapies.

This study explored the development of polymeric nanoparticles for topical spironolactone delivery, finding that larger nanoparticles (180 nm) enhanced drug targeting to hair follicles significantly more than smaller ones or non-nanoparticle formulations, offering promise for safer acne and alopecia treatments.

In this study involving a mouse model, researchers reported that intranasal delivery of protein-based CRISPR/dCas9 nanoparticles targeting the gene *Sirt1* reduced cerebral edema and increased survival following ischemic stroke, with no significant toxicity observed.

This article organizes and lists ongoing and completed clinical trials of novel agents for lung cancer, serving as a reference tool with no new research findings reported.

This study found that erythrocyte-anchored CPA-encapsulated nanoparticles improved the delivery and accumulation of Cepharanthine in the lungs, enhancing its effectiveness in treating acute lung injury by reducing inflammatory responses.

This study found that lineage-restricted loss of p63 in murine thymic epithelial cells resulted in severe thymic hypoplasia and absence of hair follicles, indicating p63's critical role in thymic and hair follicle development.

This study reviews current treatments for alopecia areata, highlighting that despite various options like corticosteroids and immunosuppressives, their limited efficacy and potential side effects are challenges, while targeting specific cytokines has shown promise except with TNF inhibitors, which may worsen the condition.

This research review identified improved outcomes in acne treatment when oral probiotics or topical probiotic-derived formulations were added to standard therapies, with probiotics reducing acne severity and enhancing safety and tolerability compared to treatments such as 2.5% Benzoyl Peroxide and Doxycycline.

This review found that adding immune checkpoint inhibitors to cancer treatment regimens likely increases the incidence of specific drug-related skin toxicities in adult Asian patients, highlighting the need for careful monitoring and management strategies.