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This study found that activating the erbB-2 oncogene in transgenic mice led to severe skin abnormalities and fatal defects, indicating erbB-2's significant role in skin and hair follicle development.

This review outlines dermatological toxicities associated with targeted cancer therapies and immunotherapies, emphasizing the need for collaborative management by oncologists and dermatologists but reports no new clinical findings.

This study found that polymeric nanoparticle suspensions can deliver poorly water-soluble drugs to hair follicles in animal models, suggesting a promising method for targeted topical treatments.

This study found that artocarpin delivered via alginate/chitosan microparticles effectively suppressed the growth of hamster flank organs compared to artocarpin in solution form, without significant systemic effects.

In this study, gene inactivation in mouse hair follicle stem cells lacking ILK impaired wound healing by reducing their progeny’s contribution to the regenerating epidermis, but did not affect hair follicle regeneration.

This review discusses recent developments in targeted melanoma therapies, including BRAF/MEK/ERK pathway inhibitors and challenges like resistance and skin toxicities, but reports no new clinical results.

This review details how zinc pyrithione's anti-fungal activity makes it a successful treatment for dandruff and seborrheic dermatitis, by effectively targeting Malassezia yeast in the scalp.

This study found that targeting SV40 T antigen expression to hair follicles in transgenic mice caused abnormal hair structure and hair loss, but did not lead to cell immortalization or tumor formation in follicles.

This study demonstrated a method for delivering a photosensitizer, Ammi majus fructuum furocumarines, into hair follicles using calcium carbonate particles, followed by UVA irradiation, which led to significant pigment accumulation, indicating potential improvements for photochemical therapy.

This review highlights challenges in developing drugs targeting the Wnt/β-Catenin signaling pathway for cancer due to its complexity and essential roles in normal tissue. It explores targeted protein degradation technology as a promising strategy to overcome these challenges, suggesting potential new avenues for drug development.

This study observed that the genes WNT7A, CASP7, and TNF were overexpressed in early stages of androgenetic alopecia, suggesting involvement of the WNT pathway, apoptosis, and inflammation in the disorder's development.

This review discusses the cutaneous side effects of targeted anticancer therapies, such as rashes and hair changes, but presents no new clinical results.

This study suggests that label-retaining cells in the hair follicle contribute to follicular renewal, indicating a specific role in the hair cycle by proliferating during the late telogen phase.

This review discusses recent preclinical strategies for enhancing mesenchymal stem cell delivery to ischemic cardiac and peripheral tissues but reports no clinical results.

This systematic review reports that prophylactic minocycline and pyridoxine may reduce certain skin toxicities in cancer patients, but evidence quality for various interventions was limited and future research is needed.

This review explores molecular targets for head and neck squamous cell carcinoma and discusses potential advancements in radiopharmaceuticals for targeted radionuclide therapy, reporting no new clinical results.

This study found that nutritional supplementation with hydrolyzed collagen, amino acids, vitamins, and minerals significantly improved hair anagen/telogen ratios and hair density in telogen effluvium patients.

This study established that the Dct::CreERT2 mouse line is effective for targeting and studying adult melanocyte stem cells, contributing to the understanding of melanocyte biology and hair pigmentation.

This study observed that combining targeted UVA phototherapy with topical 8-methoxypsoralen showed cosmetically acceptable hair regrowth in patients with patchy alopecia areata.

Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

This study found that nanoemulsions containing oleic acid or eucalyptol significantly enhanced the skin penetration of caffeine and naproxen compared to aqueous solutions, primarily by increasing solute diffusivity in the stratum corneum.

This study reports that targeted anticancer therapies frequently cause skin-related side effects, which may impact patient adherence and quality of life, but these effects are positively correlated with treatment response.

This chapter discusses photodynamic therapy and its potential applications beyond cancer treatment, including conditions like alopecia and angina, but reports no new clinical findings.

This article reviews skin toxicity classifications and management in patients undergoing molecularly targeted therapy, noting significant dermatotropic side effects associated with Epidermal Growth Factor Receptor Inhibitors.

This study introduces the MHS Hair Restoration Protocol, a systems-biology model targeting hair follicle health through the gut-microbiome-endocannabinoidome axis and innovative topical treatments, emphasizing a holistic approach to pattern hair loss.

This research introduces the MHS Hair Restoration Protocol, which is a comprehensive approach aimed at restoring the hair follicle environment by modulating the gut-microbiome-endocannabinoidome axis and incorporating specific dietary and topical strategies, rather than focusing only on short-term hair count improvements.

In this study, a liposomal-encapsulated Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss over 180 days, showing enhanced hair density, thickness, growth rate, and tensile strength compared to placebo, with no related adverse events reported.

This study found that the liposomal Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss compared to placebo over 180 days, enhancing factors such as hair density, thickness, growth rate, and tensile strength, with no related adverse events reported.

Nanocarriers with spironolactone and 2-deoxy-D-ribose may improve hair loss treatment by targeting hair follicles directly.

In this study, researchers observed that using an Avena strigosa seed extract on chemically damaged hair significantly improved hair properties, including strength, gloss, and surface quality, by reinforcing keratin bonding and sealing cuticle damage.