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Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Low testosterone does not prevent prostate cancer in men with type 1 diabetes.

Finasteride effectively treats BPH, but needs more trials to understand potential.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

A woman developed male traits from accidental contact with her husband's testosterone gel.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.

A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Finasteride reduces hair growth better, but spironolactone has more side effects.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.