TLDR Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
The study investigated the effects of subcutaneous testosterone implants in women, involving 154 pre- and post-menopausal women in Group 1, 12 postmenopausal women in Group 2, and a single patient in Group 3. It found that testosterone levels at week 4 post-implantation were significantly higher than natural levels, with considerable individual variance. When symptoms returned, levels were lower but still above natural levels. The study concluded that pharmacological dosing of testosterone implants is necessary to achieve physiological effects in women, and treatment should be based on safety, tolerability, and clinical response rather than a single testosterone measurement due to its variability. The study also noted that testosterone therapy increased scalp hair growth without causing androgenic alopecia and was generally well-tolerated, with over 16,000 implant procedures performed safely.
21 citations,
October 2011 in “British Journal of Dermatology” Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.
81 citations,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
10 citations,
April 2006 in “Seminars in Reproductive Medicine” Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
37 citations,
February 2013 in “Maturitas” Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
21 citations,
October 2011 in “British Journal of Dermatology” Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.
2 citations,
April 2023 in “Pharmaceuticals” Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.
20 citations,
April 2021 in “Journal of Womens Health” Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
81 citations,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
