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Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

A protein from fat-derived stem cells, DKK1, is linked to hair loss and blocking it may help treat alopecia areata.

Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.

Hemp seed biomaterials may reduce hair loss and improve hair growth.

Adenosine can help treat hair loss by promoting hair growth.

Stress may trigger hair loss by affecting immune protection in hair follicles.

The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.

Certain KIR genes in Indian SLE patients are linked to disease severity and could be biomarkers.

Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.

The role of γδT-cells in causing alopecia areata remains unclear.

Muscles and nerves that cause goosebumps also help control hair growth.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Fat-related cells are important for initiating hair growth.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Different types of skin cells play specific roles in development, healing, and cancer.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.