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Brodalumab effectively treated a man's severe hand and foot psoriasis.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

PPAR-γ may be a key target for treating alopecia areata and other skin conditions.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.

A mother and son both had ulcerative colitis and alopecia, suggesting a genetic link in autoimmune disorders and successful treatment with cyclosporine.

Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.

Alopecia areata patients have higher levels of IL-6 and TNF-α.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

Certain genetic variants linked to immune response increase the risk of alopecia areata in Taiwanese people.

Taking vitamin D might improve life for MS patients and reduce skin side effects from alemtuzumab treatment.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Cell aging can be both good and bad for tissue repair.

Alefacept showed some effectiveness for alopecia areata but needs more research.

Testosterone's effects on COVID-19 are unclear and need more research.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

A woman lost all her hair after mild COVID-19, but it started to regrow after treatment with a specific medication.

Xiangdong black goats have moderate genetic diversity, minimal inbreeding, and important genes for reproduction, immunity, and other traits.

These specific gene polymorphisms are not linked to Alopecia Areata in Egyptians.

SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.

NOC-4 extract promotes black hair and hair growth effectively.