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The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.

Women with PCOS have more insulin resistance and are more likely to have heart-related health issues, with insulin resistance being a bigger factor than β-cell problems.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.

Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.

Metabolism plays a key role in determining stem cell fate.

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Cytotoxic T cells cause hair loss in chronic alopecia areata.

Hair follicle regeneration possible, more research needed.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Using bioreactors, scientists can grow more skin stem cells that keep their ability to regenerate skin and hair.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.

Softer hydrogel surfaces help maintain hair growth-related functions in skin cells.

SOX9 is essential for the development of various organs and hair follicles.

White hair follicles in vitiligo have fewer and less functional melanocytes.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Vitamin D and calcium are important for skin stem cell function and wound healing.