41 citations
,
September 2018 in “Australasian journal of dermatology” This review suggests that oral prednisolone pulse therapy and oral inosiplex may be effective for alopecia areata, but robust evidence from randomized controlled trials is lacking, highlighting the need for better-designed future studies.
15 citations
,
November 1997 in “Australasian Journal of Dermatology” This report describes a case where a patient with acute generalized pustular psoriasis achieved remission using a combination of oral cyclosporin and PUVA therapy, maintaining remission 12 months after stopping treatment.
13 citations
,
April 2020 in “Dermatology and therapy” This systematic review assessed cyclosporine's effectiveness with or without corticosteroids for treating alopecia areata, finding combined therapy more effective and with a lower recurrence rate than monotherapy, especially for severe cases, though results varied by alopecia type.
8 citations
,
January 2008 in “Annals of Dermatology” This study concluded that combining systemic cyclosporine A with low-dose corticosteroids effectively treats severe alopecia areata while maintaining safe cyclosporine A levels in the blood.
5 citations
,
May 2023 in “Frontiers in immunology” This review discusses how environmental factors like lifestyle, nutrition, and vitamin deficiencies may influence autoimmune diseases such as MS, SLE, and AA, highlighting associations with vitamin D levels and dietary interventions, but notes a lack of conclusive evidence for their roles in disease pathogenesis.
22 citations
,
April 1998 in “Dermatologic Clinics” This article reviews the therapeutic use of interferons and other cytokines in various viral, tumorous, and inflammatory diseases, discussing their biological effects and potential future applications without presenting new experimental results.
118 citations
,
April 1998 in “Dermatologic Clinics” This review discusses the advancements in understanding and treating androgenetic alopecia and alopecia areata but reports no clinical findings; the authors emphasize the need for further research on molecular control mechanisms.
71 citations
,
March 2009 in “Seminars in cutaneous medicine and surgery” This review discusses evidence for alopecia areata treatments, highlighting their ability to stimulate hair growth but noting limited data on long-term efficacy and impact on quality of life.
24 citations
,
March 2009 in “Archives of dermatological research” This study found that a combination therapy of oral corticosteroid and oral PUVA led to scalp hair regrowth in patients with intractable alopecia totalis and universalis within two months.
10 citations
,
May 1983 in “International Journal of Dermatology” This study found that four out of ten patients with alopecia areata experienced some hair regrowth after PUVA therapy, though this treatment should be reserved for those unresponsive to other options due to potential long-term side effects.
281 citations
,
January 2013 in “British Journal of Dermatology” Manage vitiligo with treatments, address emotions, and use camouflage techniques.
2 citations
,
January 2009 in “Actas Dermo-Sifiliográficas” This article reviews various treatments for scalp psoriasis, emphasizing the effectiveness and long-term safety of combining potent corticosteroids with vitamin D3 analogues, but reports no new clinical results.
5 citations
,
November 2011 in “Expert Review of Dermatology” This review discusses the causes, diagnosis, and treatment of pediatric alopecia, emphasizing early diagnosis and considering holistic approaches, but reports no new clinical results.
218 citations
,
April 2012 in “British Journal of Dermatology” This updated guideline from the British Association of Dermatologists discusses current recommendations for managing alopecia areata but reports no new clinical research findings.
277 citations
,
December 2019 in “Frontiers in Immunology” This review discusses the immunological basis and development of Janus kinase inhibitors for treating skin diseases and reports no new clinical findings.
208 citations
,
July 2001 in “Journal of The American Academy of Dermatology” This review discusses the classification and diagnosis of pregnancy-related skin conditions and reports no new clinical findings.
122 citations
,
November 1984 in “Journal of the American Academy of Dermatology” This review discusses the potential autoimmune pathogenesis and various contributing factors of alopecia areata, noting that current treatments remain palliative while emerging therapies offer new hope for extensive cases.
108 citations
,
November 1980 in “British Journal of Dermatology” This article reviews the current status of oral retinoids in dermatology and reports no new clinical findings.
85 citations
,
October 2012 in “Dermatologic Clinics” This article reviews recent updates on alopecia areata, focusing on its causes, clinical presentation, and treatment options, and provides treatment plans by patient age and disease extent, but reports no new clinical results.
68 citations
,
May 2012 in “Annals of Oncology” This study reports that permanent and severe alopecia is a newly identified complication of the FEC 100–docetaxel regimen used for adjuvant breast cancer treatment.
59 citations
,
June 2022 in “Frontiers in medicine” This review discusses the complex causes and treatment challenges of chronic inflammatory skin diseases, emphasizing the need for biomarkers to predict treatment responses; it reports no new clinical results.
52 citations
,
June 1981 in “International Journal of Dermatology” Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
49 citations
,
November 1992 in “Archives of dermatology” This article discusses the emotional and psychological impact of severe alopecia areata on patients, emphasizing feelings of loss, vulnerability, and self-identity changes, and reports no new results.
48 citations
,
October 1996 in “Dermatologic clinics” This review discusses the variability and limitations of treatments for severe alopecia areata, noting some patients may achieve cosmetic hair regrowth with treatment, while others experience persistent hair loss or relapse.
42 citations
,
January 2007 in “Pediatric dermatology” This report describes an 11-year-old boy with Netherton syndrome who developed Cushing syndrome after using low-potency hydrocortisone ointment extensively, highlighting caution with long-term topical treatments in such conditions.
37 citations
,
June 2018 in “Clinical and Experimental Medicine” This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.
35 citations
,
May 2012 in “Expert Opinion on Pharmacotherapy” This review summarizes current and emerging treatments for common hair loss conditions, highlighting good evidence for androgenetic alopecia but noting the lack of long-term data for alopecia areata and cicatricial alopecias.
34 citations
,
April 2009 in “Expert Opinion on Pharmacotherapy” This review discusses evidence-based treatments for common hair loss forms, noting robust support for androgenetic alopecia therapies but limited long-term data and fewer high-quality studies for alopecia areata and cicatricial alopecias.
24 citations
,
July 2019 in “Cochrane library” This review found that oral methotrexate plus oral prednisone may improve disease activity or damage in juvenile active morphea compared to placebo plus prednisone, but adverse events may slightly increase.
24 citations
,
March 2018 in “Experimental Dermatology” This review explores the role of regulatory T cells in autoimmune skin disorders like alopecia areata and vitiligo, emphasizing unanswered questions and reporting no new experimental results.