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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

Dermatologists need to understand African American hair-care practices to better treat their hair and scalp disorders.

Tph cells are linked to the severity of systemic lupus erythematosus.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

The guide explains how to identify and treat children's hair loss, including fungal infections, autoimmune disorders, hairstyle changes, self-correcting conditions, and behavioral therapy for hair-pulling.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

People with depression often have higher hair cortisol levels, while those with PTSD tend to have lower levels, but more research is needed to understand this fully.

Hair loss in lupus patients indicates higher disease activity.

Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.

Most patients with Systemic Lupus Erythematosus experience fatigue, skin issues, and joint pain.

SLE patients with Evans syndrome often show blood issues and need careful monitoring and treatment.

Special and immunohistochemical stains are not routinely needed for diagnosing hair disorders.

Early diagnosis and quick treatment are crucial for severe lupus cases.

Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.

WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.

HIV can cause skin disorders, which are often the first sign of infection, especially in people with darker skin.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

A family showed a new condition with inherited hair loss and skin changes, possibly due to one genetic disorder.

Certain genetic markers can indicate higher or lower risk for systemic lupus erythematosus.

The book provides updated knowledge on hair disorders and new treatments for hair loss.

Early recognition and management of connective tissue diseases like lupus are crucial in young patients.

Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.

Hair shedding after COVID-19 is more linked to the disease's severity and inflammation rather than hormones, with women at higher risk.

A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.

Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.

Hydroxychloroquine effectively treated a woman's lupus skin issues and hair loss.

The conclusion is that careful management of both psychiatric and skin conditions is crucial for HIV patients, using medication and interdisciplinary approaches.