research Wnt Signaling Activation: Targets and Therapeutic Opportunities for Stem Cell Therapy and Regenerative Medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
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research Cutaneous Toxicities of New Targeted Cancer Therapies: Must Know for Diagnosis, Management, and Patient-Proxy Empowerment
New targeted cancer drugs can cause skin side effects, and managing them requires patient education and timely care.
research Growth Factor Mimetics for Skin Regeneration: In Vitro Profiling of Primary Human Fibroblasts and Keratinocytes
SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.
research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
research Exosomes for Repair, Regeneration, and Rejuvenation
Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
research Therapeutic Anti-Inflammatory Potential of Formyl-Peptide Receptor Agonists
Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
research The Emerging Role of Janus Kinase Inhibitors in the Treatment of Autoimmune and Inflammatory Diseases
Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
research Spatiotemporal Control of CRISPR/Cas9 Gene Editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research Plant Hormones: The Outlook for Their Application
Plant hormones have potential in agriculture to increase food production but require more research for effective use.
research JAK Inhibitors: New Players in the Field of Immune-Mediated Diseases Beyond Rheumatoid Arthritis
JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
research Mechanism of Action of Bolandiol (19-Nortestosterone-3β,17β-Diol), a Unique Anabolic Steroid with Androgenic, Estrogenic, and Progestational Activities
Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.
research Nanomaterial-Based Therapy for Wound Healing
Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.
research Latanoprost-Loaded Nanotransfersomes Designed For Scalp Administration Enhance Keratinocytes Proliferation
Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.
research Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research Role of Regeneration in Tissue Repairing and Therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
research Nanofiber Scaffolds as Drug Delivery Systems Promoting Wound Healing
Nanofiber scaffolds help wounds heal by delivering drugs directly to the injury site.
research Pharmacological Activity Of Cepharanthine
Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
research The Clock Within: Molecular Clock in Epidermis Regulates Circadian Rhythms and Stem Cell Cycles
The circadian clock in skin cells controls their growth and rest cycles.
research Selective Induction of Apoptosis in the Hamster Flank Sebaceous Gland Organ by a Topical Liposome 5-Alpha-Reductase Inhibitor: A Treatment Strategy for Acne
A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
research Hair Follicle Culture
Hair follicle culture helps study hair growth but has limitations in modeling the full hair cycle.
research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
research HDL as Therapeutic Tools
Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
research Plants Used in Cosmetics
Natural products in cosmetics are beneficial for skin and hair care with low toxicity.
research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane
The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.
research Sulfotransferases, Sulfatases, and Formylglycine-Generating Enzymes: A Sulfation Fascination
The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.
research A Review on Jasmonic Acid and Its Derivatives
Jasmonic acid and its derivatives play important roles in plant health and have potential uses in medicine and agriculture.
research Topical Delivery of Protein and Peptide Using Novel Cell Penetrating Peptide IMT-P8
The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.
research LPA3, A Unique G Protein-Coupled Receptor For Lysophosphatidic Acid
LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Antibody-Capped Mesoporous Nanoscopic Materials: Design of a Probe for the Selective Chromo-Fluorogenic Detection of Finasteride
Probe detects finasteride with high selectivity and low detection limit.