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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

Spironolactone safely and effectively treats hair loss in female scarring alopecia patients.

Platelet-Rich Plasma may improve skin health and reduce wrinkles, but more research is needed for standard treatment guidelines.

Nirmatrelvir/Ritonavir treatment may lead to a weaker immune response to COVID-19, but doesn't affect the chance of rebound.

A new vaccine using a porous scaffold boosts immunity and protects against the flu better than traditional methods.

Targeted anticancer therapies in children often cause skin side effects like rash and dry skin.

The trial aims to test if spironolactone is an effective acne treatment for women without the side effects of current treatments.

Taking too much vitamin E caused a young man's blood clotting problems, which improved after he stopped the vitamin E and got treatment.

Metformin is less effective in men with early-onset hair loss.

Fibronectin-attached cell sheets improve wound healing and are safe and effective.

Different types of PCOS need specific diagnosis methods and treatments.

Artificial sebum L closely mimics human sebum for drug delivery research.

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

A new method efficiently modifies alkenes to create useful medicinal compounds.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Researchers found 15 new genetic links to skin traits in Japanese women.

Tofacitinib, an arthritis drug, helped hair growth in alopecia universalis but long-term safety needs more research.

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.

Nicotinamide applied to the scalp can slow down hair growth.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.