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DermaCult™ Keratinocyte Expansion Medium allows human skin cells to grow longer while keeping their ability to develop properly.

Hox proteins help maintain keratinocyte identity by regulating miRNA expression.

The skin and thymus develop similarly to protect and support immunity.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.

Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.

The method increases stem-like cells for better skin regeneration.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Transglutaminase activity is important for skin and is found in both mammals and birds.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

The CUBIC protocol allows detailed 3D visualization of proteins in mouse skin biopsies.

Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Skin diseases are common and can significantly affect people's lives; better outcome measures and ethical clinical trials are needed to improve dermatology care.

The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.

Mitochondrial reactive oxygen species are essential for skin and hair development.

TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.

Retinoic acid helps change skin cells and is important for skin development and hair growth.

Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.

Multiple mouse desmoglein 1 isoforms have distinct roles in skin and hair development.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

Epidermal stem cells show promise for treating orthopedic injuries and diseases.

Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

K16 can partially replace K14 but causes hair loss and skin issues.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.