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    Glossary Steroidogenic Enzymes

    specialized proteins that produce steroid hormones from cholesterol

    Steroidogenic enzymes are specialized proteins in the body that help produce steroid hormones, such as cortisol, estrogen, and testosterone. These enzymes facilitate chemical reactions that convert cholesterol into these hormones, which are crucial for various bodily functions like stress response, reproductive health, and metabolism.

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    Research 30 of 661

    1. Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1) Journal of Investigative Dermatology · 2003 · 289 citations
    2. Steroidogenic enzymes in skin. PubMed · 2001 · 21 citations
    3. Sex-Chromosome-Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells International journal of molecular sciences · 2023
    4. Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes edoc (University of Basel) · 2014
    5. Effect of perfluorooctanesulfonate exposure on steroid hormone levels and steroidogenic enzyme activities in juvenile <i>Silurana tropicalis</i> 2019 · 4 citations
    6. Expression of steroidogenic enzymes in human sebaceous glands 2014 · 25 citations
    7. New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway Current Enzyme Inhibition · 2022
    8. Is dehydroepiandrosterone a hormone? Journal of Endocrinology · 2005 · 403 citations
    9. Polycystic ovarian syndrome: Correlation between hyperandrogenism, insulin resistance and obesity Clinica Chimica Acta · 2019 · 195 citations
    10. Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice Pharmacology Biochemistry and Behavior · 2008 · 66 citations
    11. Enzymology of the hair follicle. PubMed · 2001 · 31 citations
    12. Congenital adrenal hyperplasia Dermatologic Therapy · 2008 · 16 citations
    13. Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats Pharmacology Biochemistry and Behavior · 2010 · 13 citations
    14. Prevention of Male Late-Onset Hypogonadism by Natural Polyphenolic Antioxidants Nutrients · 2024 · 12 citations
    15. Development of prostate cancer in a patient with primary hypogonadism: intratumoural steroidogenesis in prostate cancer tissues Andrology · 2012 · 10 citations
    16. Mild Cutaneous Manifestation in Two Young Women with Extraordinary Hyperandrogenemia Dermatology · 2004 · 5 citations
    17. Effect of <i>Eurycoma longifolia</i> Extract on Testosterone Synthesis in TM3 Leydig Cells under Oxidative Stress 2022 · 1 citations
    18. Disruptors of Androgen Action and Synthesis Elsevier eBooks · 2015 · 1 citations
    19. The impact of minoxidil on male reproductive biology: a multi-approach study including systematic review, in vivo, and ex vivo experiments 2025
    20. Steroidogenesis in steroid related cancers University of Birmingham Institutional Research Archive (University of Birmingham) · 2016
    21. Protective Effect of “ <i>Ark‐e‐Kasni</i> ,” a Unani Formulation, in Letrozole and High‐Fat Diet–Induced Polycystic Ovarian Syndrome in Rats Journal of obstetrics and gynaecology research · 2026
    22. Palmitoylethanolamide Stimulation Induces Allopregnanolone Synthesis in C6 Cells and Primary Astrocytes: Involvement of Peroxisome-Proliferator Activated Receptor-α Journal of Neuroendocrinology · 2011 · 52 citations
    23. Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia Dermatology · 2003 · 31 citations
    24. Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development General and Comparative Endocrinology · 2009 · 60 citations
    25. Repurposing steroidogenesis inhibitors for the therapy of neuropsychiatric disorders: Promises and caveats Neuropharmacology · 2018 · 10 citations
    26. [Hormonal interaction and hair growth]. PubMed · 2002 · 15 citations
    27. Search for New antineoplastic agents based on structural modifications of steroidal 5α-reductase, 17β-hydroxysteroid dehydrogenase, and 17α-hydroxylase/17,20-lyase inhibitors Russian Journal of Oncology · 2025
    28. Skin steroidogenesis in health and disease Reviews in endocrine and metabolic disorders · 2016 · 47 citations
    29. Midazolam Ameliorates the Behavior Deficits of a Rat Posttraumatic Stress Disorder Model through Dual 18 kDa Translocator Protein and Central Benzodiazepine Receptor and Neurosteroidogenesis PLoS ONE · 2014 · 56 citations
    30. Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects Neuropharmacology · 2017 · 25 citations