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Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Methotrexate is not proven to maintain remission in ulcerative colitis.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Adrenal disorders can cause lasting brain and behavior issues in children.

Some IBD patients on anti-TNFs developed severe skin issues, but ustekinumab helped.

The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.

Mycophenolate mofetil can effectively treat autoimmune hepatitis when standard drugs fail.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Steroid use can cause a rare eye condition called central serous retinopathy, which can lead to permanent vision damage.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

A woman with a drug allergy to anakinra was successfully desensitized, allowing her to continue treatment without allergic reactions.

Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.

Skin problems from transplant drugs are common and need careful management in organ transplant patients.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Accidentally eating a topical steroid may rarely cause acute generalized pustular psoriasis.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Gut microbes significantly affect brain steroid levels.

Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.