Mycophenolate Mofetil as an Alternative Treatment for Autoimmune Hepatitis
June 2016
in “
Clinical and Molecular Hepatology
”
Studysummary This case report describes an autoimmune hepatitis patient who achieved remission with mycophenolate mofetil and corticosteroids after intolerance to azathioprine-based therapy. Our plain-language summary of this paper — not a Tressless recommendation.
Autoimmune hepatitis (AIH) is a chronic liver disease treated with corticosteroids and azathioprine, but some patients do not respond due to drug intolerance or refractory disease. Mycophenolate mofetil (MMF) has been used as an alternative when azathioprine is not tolerated, although evidence for its efficacy is limited. This report described a patient with AIH who did not achieve remission with the standard regimen due to azathioprine side effects but was successfully treated with MMF and corticosteroids.
