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Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

A man's health improved after treating his undiagnosed adrenal insufficiency, which caused fatigue and weight loss.

Androstenedione is better than testosterone for diagnosing PCOS in Indian women.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Androgens significantly affect female hair loss, and hormonal treatments may help.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

Birth control pills can cause skin issues but may help with acne and hirsutism, and choosing the right type can minimize side effects.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.