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This study reported no evidence that clomipramine reduces overgrooming or improves hair regrowth in cats with psychogenic alopecia compared to untreated cats.

This study found that self-supervised pretraining significantly improves accuracy in medical image classifiers for dermatology and chest X-ray tasks, outperforming supervised baselines and showing robustness to distribution shifts with limited labeled data.

This research by Yuan et al. focused on developing a comprehensive human skin cell atlas, analyzing various cell types and diseases, and introduced a deep learning method, scSEA, for unbiased reference mapping, potentially discovering new cell types.

In this study, researchers developed a non-invasive, partially automated protocol for extracting DNA from marmoset hair follicles, resulting in high-quality whole genome sequencing with low chimerism levels, making it a reliable method compared to blood DNA sequencing in these primates.

This study developed and validated a high-resolution mass spectrometry method to screen for prohibited substances and analyze six endogenous steroids in urine according to World Antidoping Agency requirements, demonstrating its effectiveness for antidoping analysis.

This review highlights advancements in applying single-cell sequencing to cattle, sheep, and goats, noting its potential to elucidate cellular diversity and improve traits affecting livestock health and productivity, despite challenges in cell population annotation and spatial resolution in these species.

This study generated a transcriptomic map of human hair follicles, identifying compartment-specific gene expression profiles that can aid in developing targeted therapies for hair follicle disorders.

This study highlighted the significance of integrating single-cell RNA sequencing with spatial transcriptomics for improving cell-type identification in human skin, emphasizing the need for a comprehensive cell atlas.

This study validated a protocol for inducing surface ectoderm differentiation from human induced pluripotent stem cells and highlighted the role of TGFβ signaling pathways in this process.

This research examined the transcriptional landscape of quiescent melanocyte stem cells (qMcSCs) in adult female mice, revealing significant heterogeneity within this cell population and identifying novel subpopulations that vary in immune privilege regulation, melanocyte differentiation potential, and neural crest potential.

In this study, researchers used genomic, metabolomic, and transcriptomic methods to explore the biosynthetic capabilities of S. longa, aiming to better understand the species and lay the groundwork for future studies on the biosynthesis and therapeutic use of cepharanthine and similar alkaloids.

This study developed a new STR typing strategy for forensic casework, enabling the simultaneous analysis of 11 polymorphic systems, particularly useful for limited or degraded DNA samples such as telogen hair roots.

This study developed a partially automated protocol utilizing hair follicles for DNA extraction in marmosets, achieving reliable whole genome sequencing with low chimerism, offering an efficient alternative to blood for genetic studies in non-human primates.

This study developed a novel smart deoxyribozyme-based fluorescent sensor that efficiently detects androgen receptor mRNA with high selectivity and can be adapted to target various nucleic acid sequences.

This study found that super-enhancers in squamous cell carcinoma stem cells are distinctly different from those in normal skin stem cells, with ETS2 playing a crucial role in promoting tumor growth.

In this study, the authors developed a modified alkaline-based proteomics protocol that improved the reproducibility of detecting hair proteins, potentially aiding future biomarker discovery.

This study demonstrated that combining cell conditioning with mild protease digestion enhanced the visualization of versican mRNA in formalin-fixed mouse skin tissue sections compared to using either technique alone.

In this study, elevated mRNA levels for serine-rich ultra high sulfur proteins were observed during active hair growth phases in mice, particularly in the forming hair structures and upper skin layers.

This study presents a new method called scMC that effectively distinguishes biological from technical variation in single-cell genomics datasets, demonstrating its ability to accurately align and detect biological signals across various experiments.

This study introduced rPanglaoDB, an R package that facilitates the integration of public scRNA-seq datasets to effectively characterize rare cell types, exemplified by generating the first unbiased transcriptome profile of fibrocytes.

This study investigated dual TCR Treg cells in mouse tissues, revealing a high proportion and diverse pairing patterns compared to single TCR Tregs, providing insights into their origins and characteristics across different tissue locations.

This study analyzed the transcriptome of the Tianzhu white yak, identifying differential transcripts that shed light on the molecular mechanisms influencing hair length growth variation in this species.

This study highlighted the effectiveness of HT-scCAT-seq as a tool for understanding gene regulation in single cells, offering insights into embryonic skin development and proposing a framework for exploring regulatory mechanisms in various biological and disease contexts.

This study developed and validated a mass spectrometric method to measure hydroxy-androgens in serum, which aids in understanding androgen synthesis in castration resistant prostate cancer.

This study identified highly variable genes in mesenchymal stem/stromal cells that are linked to classic functions like development and inflammation response, suggesting their potential as markers for further potency studies.

In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.

This study identified specific gene expression profiles during the intestinal regeneration of sea cucumbers, highlighting potential novel genes and advancing the understanding of regenerative biology in echinoderms.