May 2024 in “Scientific reports” This study explored the role of Twist2 in fetal wound healing in embryonic mice, observing that its expression was vital for scarless regeneration and normal hair follicle formation; Twist2 knockdown led to visible scars and defective follicle formation.
April 2024 in “ScienceRise. Pharmaceutical science” In this study, conducted through a survey in Ukraine, researchers found that 48.7% of men believe androgenic alopecia negatively affects their emotional state and quality of life, with approximately 90% expressing the need for more effective treatments on the market.
March 2024 in “Research Square (Research Square)” In this study, researchers found that the protein Twist2 plays a crucial role in scarless wound healing in early embryonic mouse skins, with its knockdown leading to visible scarring and defective hair follicle formation, suggesting potential therapeutic targets for reducing scars and promoting regeneration.
May 2023 in “Journal of pharmacognosy and phytochemistry” This study conducted a comprehensive pharmacognostic and phytochemical analysis of Sphagneticola calendulacea stem, identifying tannin-filled cells, various secondary metabolites, and significant physicochemical characteristics, which could aid in authenticating the plant for therapeutic use.
December 2022 in “Jurnal Kesehatan Jompa” This article reviews the causes and current treatment options for androgenetic alopecia, reporting no new clinical findings and highlighting the need for more therapeutic choices.
May 2022 in “Journal of pharmacognosy and phytochemistry” This study carried out a detailed pharmacognostic and phytochemical analysis of Sphagneticola calendulacea leaves, which may help authenticate this plant used in treating inflammation and alopecia.
September 2020 in “Kocatepe Veterinary Journal” This study suggests that equine adipose tissue stem cells may be a promising option for cellular regenerative therapy in equines due to their differentiation capabilities and proliferation potential, but further molecular characterization is needed.
April 2019 in “Advances in Cosmetic Surgery” The document concludes that ongoing medical therapy is crucial for preventing hair loss, and surgical options can restore hair, with future treatments for hair loss being promising.
January 2016 in “Georg Thieme Verlag eBooks” Hair transplantation in East Asians needs special techniques to ensure natural results and prevent complications due to their unique hair and scalp characteristics.
September 2013 in “Molecular Biology” This study found that Satura Rosta Balm exerts a cytotoxic effect under oxidative stress and may trigger regeneration through autophagic pathways, despite not promoting proliferation or stress resistance in human cells.
January 2012 in “Methods in pharmacology and toxicology” This review discusses the use of cultured hair follicles for studying hair growth regulation and reports the challenge of modeling the entire hair cycle in vitro.
January 1983 in “Journal of the American Oil Chemists' Society” The U.S. soybean industry wanted government help due to foreign competition, while the jojoba industry was growing and expected to stabilize.
November 2003 in “Dermatologic Surgery” This study suggests that combining drugs with hair grafts may effectively regress male androgenetic alopecia from Hamilton type V to type III when evaluated using the Dynamic Multifactorial Classification.
52 citations
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February 2021 in “Genomics Proteomics & Bioinformatics” This review explains methods for studying chromatin variation at the single-cell level using scATAC-seq and discusses integrating these measures with other omics platforms but reports no new results.
August 2024 in “STAR Protocols” This study details a step-by-step protocol for preparing mammalian skin samples, including hair follicles, for spatial transcriptomics to overcome challenges inherent in applying this technique to the skin.
2 citations
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April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that skin surface lipids contain measurable mRNAs, providing a non-invasive way to study skin diseases, with specific gene expression changes observed in atopic dermatitis patients.
13 citations
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June 2024 in “Frontiers in Genetics” This review examined genetic factors in 46, XY differences/disorders of sex development and found that whole-exome sequencing is more effective than panel sequencing for molecular diagnosis. It identified regional genetic variation and emphasized next-generation sequencing's role in detecting variants related to gonadal and androgen-related genes.
January 2026 in “Figshare” This table reports gene set enrichment analysis scores for hair follicle compartments across diseases and sampling methods, providing comparisons but no new experimental findings.
73 citations
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January 2013 in “Annals of Dermatology” This study observed that patients with various types of hair loss had significantly lower serum zinc levels compared to healthy controls, suggesting zinc disturbance may play a role in the condition.
41 citations
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January 2014 in “Annals of Dermatology” This study found that dermoscopy showed distinctive patterns for different types of alopecia, supporting its clinical usefulness for diagnosing diseases with small round or oval hairless patches on the scalp.
24 citations
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September 1996 in “Mycoses” This study found that androgenic steroids, particularly androstenedione and androstanedione, significantly reduced the growth of certain dermatophytes, suggesting hormonal influence on fungal infections in hair follicles.
22 citations
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October 2019 in “Cerebral cortex” This study found that testosterone and dihydrotestosterone are crucial for synaptic transmission and spine density in male hippocampal neurons, suggesting sex-specific effects of neurosteroids on brain development.
21 citations
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February 2015 in “Journal of Feline Medicine and Surgery” This study found that negative pressure wound therapy combined with skin grafting is a feasible method for treating soft tissue and skin defects in cats, achieving a high graft take rate and satisfactory outcomes.
19 citations
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August 2010 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses plant extracts for dermatological use, highlighting evidence that some can reduce edema in chronic venous insufficiency or help treat actinic keratoses, but it reports no new clinical results.
18 citations
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October 2012 in “Dermatologic Clinics” This article discusses primary cicatricial alopecias, a group of rare inflammatory scalp disorders resulting in permanent hair loss, and reports no new findings.
11 citations
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January 1991 in “Urology” This article reviews the potential of combining antiandrogenic and antiestrogenic treatments for BPH, highlighting aromatase inhibitors, but presents no new clinical results; further research is needed.
6 citations
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September 2024 in “Metabolism and Target Organ Damage” This review discusses the role of skin enzymes in drug metabolism and emphasizes the need for models assessing enzyme activity to evaluate the safety and bioequivalence of topical generic drugs, highlighting efforts to standardize testing protocols for transdermal products.
6 citations
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February 2013 in “Veterinary Dermatology” This case report describes the first documented occurrence of pili torti in a healthy young adult cat, marked by noninflammatory and nonpruritic symmetrical multifocal alopecia.
4 citations
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January 2016 in “Dermatology Review” This review focuses on the various skin toxicities caused by chemotherapeutic and targeted tumor therapy drugs, including rashes, keratoacanthoma, and more severe conditions like Stevens-Johnson syndrome, without presenting new clinical results.
This article reviews surgical techniques for addressing scalp defects and highlights hair restoration as a cosmetic improvement strategy, but it reports no new clinical results.