January 2022 in “Stem cell biology and regenerative medicine” Stem cell therapies show promise for hair regrowth but need more research to confirm effectiveness.
March 2021 in “Cell stem cell” Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.
143 citations,
November 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
101 citations,
April 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
80 citations,
May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
52 citations,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
45 citations,
September 2014 in “Cell Transplantation” Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.
25 citations,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
23 citations,
July 2020 in “Aging Cell” Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
18 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
13 citations,
November 2014 in “Molecular therapy” The lentiviral array can monitor and predict gene activity during stem cell differentiation.
12 citations,
January 2022 in “Cells” Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.
10 citations,
May 2020 in “Frontiers in cell and developmental biology” MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
March 2023 in “Biomedicine & Pharmacotherapy” Low oxygen conditions improve how well certain stem cells from embryos can make hair grow longer and faster.
May 2021 in “Journal of Investigative Dermatology” Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
176 citations,
April 2011 in “Science” Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.
85 citations,
March 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
43 citations,
February 2009 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
26 citations,
October 2021 in “Clinical, Cosmetic and Investigational Dermatology” The secretome from mesenchymal stem cells shows promise for treating skin conditions and improving skin and hair health, but more research is needed.
14 citations,
August 2016 in “Cell Transplantation” Neural stem cell extract can safely promote hair growth in mice.
9 citations,
November 2021 in “Frontiers in Cell and Developmental Biology” PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
4 citations,
January 2022 in “Clinics in Dermatology” Stem cells show promise for hair loss and skin treatments in aesthetics but need more research on safety and standard methods.
1 citations,
December 2023 in “iScience” A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
1 citations,
October 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids from stem cells can help study and treat skin issues but face some challenges.
1 citations,
April 2021 in “Current Stem Cell Reports” Eating less can improve stem cell function and increase lifespan.
308 citations,
September 2010 in “Nucleic acids research” Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
132 citations,
February 2013 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
41 citations,
April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.