June 2006 in “Experimental dermatology” Hair follicle bulge cells are important for hair survival and help heal the skin after injury, which might be relevant for understanding hidradenitis suppurativa.
89 citations,
November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
13 citations,
September 2014 in “Birth defects research” Human epidermal neural crest stem cells could be used for therapies, drug discovery, and disease modeling.
4 citations,
February 2020 in “Cell & tissue research/Cell and tissue research” Hair follicle stem cells might help treat traumatic brain injury.
22 citations,
August 2017 in “Stem cells and cloning” Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
7 citations,
January 2020 in “PubMed” Stem cell therapies show promise for treating hair loss, but more research is needed to understand their safety and effectiveness.
4 citations,
January 2015 in “Experimental Dermatology” Human hair follicle dermal cells can help repair damaged hair follicles.
9 citations,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
July 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle bumps with stem cells might contribute to permanent hair loss by getting disconnected due to scarring.
7 citations,
February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.
April 2012 in “Annals of Neurosciences” The document concludes that stem cell therapies lack solid proof of effectiveness, except for blood system treatments, and criticizes the ethical issues and commercial exploitation in the field.
271 citations,
May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
8 citations,
July 2022 in “BMC neuroscience” Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
6 citations,
June 2019 in “Biotechnology Letters” Gene therapy shows promise for improving wound healing, but more research is needed for human use.
23 citations,
June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
316 citations,
June 2017 in “Stem Cell Research & Therapy” Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.
22 citations,
January 2012 in “International Journal of Trichology” Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
August 2021 in “Journal of skin and stem cell” Skin symptoms could help in early COVID-19 diagnosis but more research is needed to confirm their reliability.
3 citations,
May 2022 in “Experimental Dermatology” Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.
316 citations,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
April 2018 in “Journal of Investigative Dermatology” Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
May 2023 in “Research Square (Research Square)” Blocking the HEDGEHOG-GLI1 pathway can reduce keloid growth and may be a potential treatment.
14 citations,
January 2019 in “Advances in experimental medicine and biology” Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.
3 citations,
July 2022 in “Stem Cell Research & Therapy” Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.
9 citations,
March 2011 in “Current Pharmaceutical Biotechnology” Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
6 citations,
July 2013 in “Molecular Imaging” The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.
6 citations,
May 2021 in “Stem Cell Reviews and Reports” Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.