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This review discusses the complex role of Runx family genes in regulating stem cells in blood and skin tissues and reports no new experimental results.

This review of stem cell-based tissue engineering treatments in preclinical burn wound models reports promising improvements in skin repair, suggesting potential as an enhanced therapy for burn wounds.

This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.

This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.

This review discusses manipulating the stem cell niche as a strategy in regenerative medicine to repair damaged tissues, highlighting the potential benefits and challenges but reporting no new results.

This study found that super-enhancers are essential for hair follicle stem cell identity, lineage commitment, and plasticity in mice, with SOX9 being a key regulator of these chromatin dynamics.

This review discusses the role of stem cell progeny as integral components of stem cell niches, offering feedback that may influence different stem cell systems' microenvironments, but it presents no new research findings.

This review discusses advances in understanding mammalian stem cell niches, particularly in bone marrow, tooth, and hair follicle, and highlights the potential for developing therapies targeting these niches for tissue repair.

This forum article in BMC Biology discusses evolving views on the concept of the stem cell niche, highlighting varied mechanisms and the need for better understanding of the niche's roles and functions.

This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.

This review discusses the advancements in intraoperative stem cell therapies and highlights their potential to improve hair regrowth, but it reports no new clinical results.

This review discusses recent findings on the plasticity and regulation of epithelial stem cells and reports no new experimental results.

This review discusses how circadian clocks may influence diverse physiological functions beyond their established role in daily timekeeping, but it reports no new experimental findings.

This study found that mice lacking the Sept4/ARTS gene had more hair follicle stem cells and improved wound healing, suggesting apoptosis regulation as a potential target in regenerative medicine.

This review discusses recent advances in hair follicle biology, regeneration, and tissue engineering, highlighting emerging therapeutic opportunities, and reports no new experimental results.

This article discusses the bi-compartmental organization of hair follicle stem cell niches for balancing stem cell cycling and organ growth and proposes similar structures may exist in other adult stem cell niches but reports no new experimental results.

This study established a new in vitro culture system that supports the growth and dynamic self-organization of hair follicle stem cells and their progeny, promoting a stable population equilibrium.

This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

This review discusses the potential of stem cell secretome in regenerative medicine and suggests that its paracrine effects, rather than direct cell replacement, may drive therapeutic benefits.

This study highlights that the mammalian target of rapamycin complex 2 (mTORC2)-Akt signaling axis is essential for hair follicle stem cells to return to their niche and regenerate effectively by regulating metabolic pathways.

The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.

The researchers reported that in mice, prolactin signaling in the skin epithelium inhibits hair follicle stem cell activation, promoting quiescence during periods of high serum prolactin like pregnancy and lactation.

In this study, transgenic male mice over-expressing the androgen receptor in mesenchymal stem cells showed reduced fat mass and improved glucose clearance, suggesting enhanced androgen sensitivity may alter body composition.

This review addresses the role of skin-resident adult stem/progenitor cells in skin homeostasis, disease, and cancer development, and reports no new research results.

This study suggests that canonical BMP signaling, particularly involving Smad1 and Smad5, plays a critical role in hair follicle stem cell regulation and hair morphogenesis, with distinct roles from pSmad8.

This article explores questions about dormant hematopoietic stem cells and suggests avenues for future research, but does not present new experimental results.

This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.