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The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.

Blocking JAK3 signaling can reverse hair loss from alopecia areata.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.

A protein combining parathyroid hormone and collagen helped hair regrow in mice with a hair loss condition.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Nanotechnology shows promise for better chronic wound healing but needs more research.

Smart hydrogel dressings could improve diabetic wound healing by adjusting to wound conditions and controlling drug release.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.

Inflammatory acne damages skin stem cells and reduces their growth, leading to atrophic acne scars.

Cicatricial alopecia may be caused by immune attacks on hair follicles, gland issues, or stem cell damage.

Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.

Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.

Permanent hair removal is hard, but using longer laser pulses at lower power might improve results.

Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.

Older skin has higher cancer risk due to inflammation and stem cell issues.