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A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Plumbago zeylanica extract helps hair growth and reduces a hair loss-related enzyme.

The study suggests that analyzing DNA can help treat hair loss, but more research is needed.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

DNA analysis can help tailor alopecia treatment.

The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.

Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.

Bee venom helps hair grow and may work better than some common treatments.

The plant extract and minoxidil both reduce hair loss by lowering specific gene expressions.

New genes and pathways are important for testosterone production and male sexual development.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Testosterone in human pancreas cells boosts insulin production.

Testosterone in our bodies helps increase insulin secretion from the pancreas.

*Laportea bulbifera* contains unique compounds that may help treat benign prostatic hyperplasia.

Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Male pattern baldness may be linked to prostate cancer risk.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

Higher SRD5A2 expression predicts better response to finasteride in treating urinary symptoms.

RE-ORGA, a Korean herb extract, may help prevent hair loss.

Adding Triamcinolone to the anesthetic can reduce swelling after hair transplants, and using Platelet-Rich Plasma can improve hair thickness and patient satisfaction. The SRD5A2 gene also plays a key role in the success of hair transplants.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The document suggests more research is needed to understand the link between baldness and prostate cancer.

Male-pattern hair loss is largely influenced by genetics, with key genes identified.

Personalized treatments for hair loss are becoming more effective by using genetic information.