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In this study, repressing β-catenin/Lef1 signalling in mouse epidermis led to progressive hair loss, dermal cysts, and spontaneous skin tumors with sebaceous differentiation, indicating altered keratinocyte differentiation and potential tumourigenic processes.

This clinical case study describes an aggressive squamous cell carcinoma developing within a giant epidermal cyst on the abdomen.

This article discusses the characteristics, clinical presentation, and diagnosis of calcified epidermal cysts but reports no new clinical results.

In this case study, a shih tzu dog developed comedones and epidermal cysts on the abdominal skin following laparotomy, potentially due to the implantation of epidermal fragments into the dermis during surgery.

This study found that the administration of the mutant BRAF inhibitor dabrafenib in patients with metastatic melanoma was associated with various skin lesions, including keratinocytic proliferation that sometimes showed low-grade malignancy features.

The authors diagnosed a 5-year-old Pekinese dog with keratoacanthoma with granulomatous inflammation, and the mass did not recur 5 months after surgical removal.

This study found that keratin 15 expression in trichoepitheliomas and some basal cell carcinomas suggests a link to hair follicle stem cells in the bulge.

This case report highlights the critical role of preoperative histopathology in accurately diagnosing and treating ambiguous cutaneous lesions in the ear, nose, and throat area, emphasizing that reliance solely on clinical features can lead to misdiagnosis.

This case report details a rare large epidermal cyst over the sacrumcoccygeal region in an elderly patient, which was successfully removed surgically.

HPV 60 may cause cysts and warts on the face, not just hands and feet.

This study found that cutaneous cysts most frequently appeared as epidermal cysts, with unusual locations posing diagnostic challenges that required histopathological analysis for definitive diagnosis.

This classification proposal introduces a novel system for categorizing cutaneous adnexal cysts based on their origin in the folliculosebaceous unit and sweat glands, aiming to simplify and enhance understanding of these skin lesions.

This review highlights similarities in the development of thymus and skin epidermis, reporting no new results; the authors emphasize shared molecular mechanisms despite different embryonic origins.

This study identified a genetic variant in the CTS6 gene associated with a hypotrichosis syndrome, emphasizing the significant role of cystatin M/E in hair and skin health.

This case report documents a trichofolliculoma of the upper lip in a 70-year-old woman, highlighting its clinical presentation and successful surgical removal without recurrence.

This study found that Notch signalling promotes differentiation of epidermal cells and acts as a tumour suppressor in the skin by interacting with various pathways and mechanisms.

This study introduces the term "hair matrix cyst" for a cyst with both pilomatricoma and epidermal cyst characteristics, highlighting its potential for misdiagnosis among similar skin conditions.

This review examines the origins and mechanisms of tumor initiation in common skin cancers, but does not present new experimental findings; it emphasizes the need for further research on cancer stem cells.

This paper discusses the multipotency of cyst cells and proposes that understanding molecular circuits in cyst formation could enable engineering of desired stem cell culture phenotypes, but reports no new experimental outcomes.

This study identified hair follicle stem cells as a source of squamous cell carcinoma in an inducible mouse model and proposes targeting these for future cancer therapies.

This report presents a case of molluscum contagiosum virus infection within an epidermoid cyst in a 13-year-old on long-term steroid treatment, highlighting its rare occurrence and need for histological examination for accurate diagnosis.

This study observed that benign skin tumors were more common than malignant ones, with squamous cell carcinoma being the most frequent type among malignant tumors.

This study found that loss of Apc due to K14-cre-mediated gene recombination in mice led to aberrant growth in ectodermally derived squamous epithelia, implicating its critical role in specifying epithelial cell fates during embryonic development.

This study observed that overexpression of TGF-alpha in transgenic mice led to thicker epidermis and stunted hair growth, particularly in regions with normally thick skin and low hair density.

This review examines the differentiation potential of epithelial cells from various sources in hair follicle formation, concluding that complex interactions are required for hair-specific characteristics, which were achieved in vivo but not in vitro.

This study found that skin computed tomography may effectively identify epidermoid cysts by revealing features consistent with histopathology, potentially serving as a non-invasive diagnostic alternative to biopsies.

This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.

This study observed that vitamin D receptor knockout mice exhibit impaired epidermal differentiation and progressive hair loss, suggesting the importance of the vitamin D receptor in normal skin and hair follicle development.

This study observed that the hair loss in homozygous rhino mice is associated with widening of the hair canal due to hyperkeratosis, leading to insufficient support for hair anchoring.

This study concludes that tiny infundibular cysts, rather than comedones, are the primary lesions in chloracne.