12 citations,
January 1987 in “PubMed” Low-dose spironolactone is safe and effective for treating hirsutism.
11 citations,
October 2019 in “Cancers” Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.
11 citations,
July 2019 in “The Journal of Sexual Medicine” Spironolactone might cause painful intercourse and decreased sexual arousal in women.
10 citations,
December 2020 in “Dermatologic Therapy” Minoxidil and spironolactone combo effectively treats androgenetic alopecia, improving hair density and diameter.
10 citations,
May 2020 in “Journal of The American Academy of Dermatology” Taking spironolactone doesn't increase the chance of breast cancer coming back.
10 citations,
September 2015 in “Gynecological Endocrinology” Both treatments reduced excessive hair growth in PCOS, but there was no difference in weight, hair score, hormone levels, or insulin resistance.
9 citations,
June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
9 citations,
June 2020 in “Trials” The trial aims to test if spironolactone is an effective acne treatment for women without the side effects of current treatments.
9 citations,
November 2018 in “Acta Clinica Belgica” Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.
9 citations,
March 2011 in “PubMed” Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.
8 citations,
August 2021 in “PubMed” Oral spironolactone effectively treats hair loss with mild, manageable side effects.
8 citations,
August 2020 in “Clinical and Experimental Dermatology” Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.
8 citations,
April 1988 in “Journal of endocrinological investigation” Topical spironolactone cream doesn't cause hormone-related side effects in the body.
7 citations,
January 1990 Spironolactone improved hair density and quality in women with hair loss.
6 citations,
April 2013 in “Journal of Investigative Dermatology” Spironolactone might lower the chance of getting rosacea.
6 citations,
November 1993 in “Contact dermatitis” Spironolactone in anti-acne cream can cause allergic skin reactions in some people.
6 citations,
January 1984 in “PubMed” Spironolactone treatment reduced hair growth and androgen levels in hirsute women, but the overall effectiveness was just adequate.
5 citations,
December 2020 in “Journal of The American Academy of Dermatology” Minoxidil and spironolactone improve hair density and reduce shedding in girls.
4 citations,
January 2022 in “Dermatologic Therapy” Spironolactone is useful for treating acne and other skin conditions like excessive hair growth and certain types of hair loss.
4 citations,
December 2021 in “Journal of The American Academy of Dermatology” Doctors are prescribing spironolactone more often to treat acne and skin conditions in teenagers, and it seems safe and well-tolerated.
3 citations,
July 1990 in “Acta dermato-venereologica” A man's baldness improved possibly due to a medication that blocks male hormones.
2 citations,
September 2023 in “Curēus” Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
2 citations,
September 1997 in “Journal of The European Academy of Dermatology and Venereology” Topical spironolactone effectively treats hair loss in women.
2 citations,
January 1986 in “PubMed” Spironolactone improved symptoms in women with hormonal imbalances and had few side effects.
1 citations,
June 2023 in “Cureus” Spironolactone may help improve symptoms and tear quality in dry eye disease.
1 citations,
August 2022 in “Journal of Cosmetic Dermatology” Using both 5% spironolactone and 5% minoxidil together is safe and more effective for treating hair loss.
1 citations,
July 2022 in “Journal of Drug Delivery Science and Technology” Niosomes and ethosomes can effectively carry the drug spironolactone, potentially improving treatment for hair loss and reducing side effects.
1 citations,
November 2020 in “Journal of The American Academy of Dermatology” GSK-36 downregulation with UTMD improves plaque stability in atherosclerosis treatment.
1 citations,
August 2019 in “Evidence-Based Practice” Spironolactone and finasteride are equally effective for hirsutism in transgender women.
1 citations,
May 2019 in “The Journal of Sexual Medicine” Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.