TLDR Spironolactone may help women with hidradenitis suppurativa.
This study investigates the efficacy of spironolactone in treating hidradenitis suppurativa (HS) in women, particularly those of childbearing age. Conducted at a single center, the retrospective review included 53 female patients, with 84.1% showing improvement at 3 months and 81.8% at 6 months after starting spironolactone. The study found no significant differences in treatment response based on body mass index, menstrual HS flares, irregular menses, or polycystic ovarian syndrome. Adverse events were mild and infrequent. The study suggests spironolactone may be beneficial for female HS patients, but larger prospective studies are needed to better understand predictors of treatment response and optimal dosing.
48 citations,
July 2018 in “Journal of The American Academy of Dermatology” Spironolactone helps reduce pain and lesions in hidradenitis suppurativa patients, and lower doses are also effective.
45 citations,
November 2015 in “Dermatologic Clinics” Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.
6 citations,
December 2022 in “International Journal of Molecular Sciences” Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.
11 citations,
July 2019 in “International journal of women’s dermatology” Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.
256 citations,
March 2019 in “Journal of the American Academy of Dermatology” There is no standardized treatment for hidradenitis suppurativa, and individualized plans are needed.
45 citations,
November 2015 in “Dermatologic Clinics” Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.
1 citations,
July 2021 in “Clinical and Experimental Dermatology” Finasteride helps reduce hidradenitis suppurativa symptoms in females.
