Spironolactone in Hidradenitis Suppurativa: A Single-Center Study

    March 2024 in “ International Journal of Women’s Dermatology ”
    Rahul Masson, Sarah Park, Terri Shih, Marcia Hogeling, Vivian Y. Shi, Jennifer L. Hsiao
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    TLDR Spironolactone may help women with hidradenitis suppurativa.
    This study investigates the efficacy of spironolactone in treating hidradenitis suppurativa (HS) in women, particularly those of childbearing age. Conducted at a single center, the retrospective review included 53 female patients, with 84.1% showing improvement at 3 months and 81.8% at 6 months after starting spironolactone. The study found no significant differences in treatment response based on body mass index, menstrual HS flares, irregular menses, or polycystic ovarian syndrome. Adverse events were mild and infrequent. The study suggests spironolactone may be beneficial for female HS patients, but larger prospective studies are needed to better understand predictors of treatment response and optimal dosing.
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      community Spironolactone and pregnancy planning

      in Female  2 upvotes 3 weeks ago
      A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

      community spironolactone pills to topical

      in Research/Science  6 upvotes 1 month ago
      Crushing spironolactone pills and combining them with minoxidil for topical application may be effective for hair loss, with the addition of finasteride suggested. Adding rosemary and peppermint oils can help mask the unpleasant smell.

      community Does the effect of spironolactone on androgenetic alopecia really weaken over time?

      in Female  4 upvotes 3 months ago
      Spironolactone can remain effective for a long time in treating androgenetic alopecia, but it may not completely stop hair loss. Hair loss treatments like spironolactone, finasteride, and dutasteride slow down hair loss rather than cure it, and their effectiveness can vary based on individual response and the aggressiveness of the condition.

      community Spironolactone VS dutasteride for female pattern hair loss

      in Treatment  7 upvotes 8 months ago
      Spironolactone is more potent and lowers testosterone and DHT, while dutasteride only impacts DHT. For female hair loss, checking hormones and considering treatments like oral minoxidil, spironolactone, or topical minoxidil is recommended.

      community Spironolactone, what do you think?

      in Finasteride/Dutasteride  4 upvotes 10 months ago
      A user is considering Spironolactone for hair loss but is advised against it due to its effects on testosterone. Instead, they are recommended to try finasteride at 18 and consider dutasteride if needed.

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