Spironolactone May Reduce the Risk of Incident Rosacea

    April 2013 in “ Journal of Investigative Dermatology ”
    Julia Spoendlin, Johannes J. Voegel, Susan S. Jick, Christoph Meier
    Image of study
    TLDR Spironolactone might lower the chance of getting rosacea.
    In 2013, a large population-based case-control study using the UK-based General Practice Research Database examined the effect of spironolactone on the risk of developing rosacea. The study involved 53,927 patients with a new diagnosis of rosacea and an equal number of controls without the condition. The findings indicated that spironolactone use was linked to a reduced risk of rosacea, with an adjusted odds ratio of 0.83 for spironolactone users, which decreased to 0.47 among current users at the index date. This suggested that spironolactone's anti-androgenic effects might contribute to the lower risk, though the precise mechanism was not determined. Despite being the largest study of its kind, the authors acknowledged the possibility of residual confounding factors.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 343 results

      community Spironolactone VS dutasteride for female pattern hair loss

      in Treatment  7 upvotes 2 months ago
      Spironolactone is more potent and lowers testosterone and DHT, while dutasteride only impacts DHT. For female hair loss, checking hormones and considering treatments like oral minoxidil, spironolactone, or topical minoxidil is recommended.

      community Spironolactone, what do you think?

      in Finasteride/Dutasteride  4 upvotes 3 months ago
      A user is considering Spironolactone for hair loss but is advised against it due to its effects on testosterone. Instead, they are recommended to try finasteride at 18 and consider dutasteride if needed.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes 7 months ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

      community Spironolactone topically with a try ?!

      in Research/Science  1 upvotes 9 months ago
      A 30-year-old male is considering using dutasteride and fluridil for hair loss maintenance and is curious about the effectiveness of topical spironolactone, as he cannot take finasteride. He is also planning a hair transplant.

      community Spironolactone or bicalutamide prescription

      in Treatment  4 upvotes 1 year ago
      The conversation is about someone seeking a doctor in the EU who prescribes spironolactone or bicalutamide for female pattern hair loss, as they are having difficulty finding treatment options beyond Minoxidil in Austria. They are asking for recommendations and are open to direct messages for assistance.

      community medication for hair loss spironolactone

      in Female  3 upvotes 1 year ago
      41-year-old female experienced slow hair thinning, took finasteride for a year, then switched to spironolactone. Irregular periods occurred, seeking advice on long-term side effects and considering a third medication.

    Similar Research

    5 / 1000+ results
      Hormone Therapy in Acne

      research Hormone Therapy in Acne

      24 citations, January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”
      Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
      Clinical Updates in Hair

      research Clinical Updates in Hair

      19 citations, January 1997 in “Dermatologic Clinics”
      Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
      Medications

      research Medications

      January 2016 in “Springer eBooks”
      Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.