39 citations
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December 2012 in “The American Journal of Human Genetics” This study identified mutations in the SNRPE gene that may disrupt hair growth, linking a spliceosome component to hereditary hair loss disorders.
17 citations
,
October 1997 in “Australian Journal of Agricultural Research” This study observed that nutritional stress is likely responsible for changes in Merino sheep follicle morphology in Mediterranean environments, affecting staple strength and possibly requiring targeted management strategies.
14 citations
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December 2019 in “International Journal of Phytocosmetics and Natural Ingredients” This study found that a conditioner containing Spirulina platensis and Ascophyllum nodosum extracts improved hair shine and reduced combability force after 28 days of use.
24 citations
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November 2015 in “Scientific reports” This study discovered a new region in the hair cortex where intermediate filaments are both aligned with the hair's axis and orientationally ordered, influenced by the cuticle boundary.
April 2024 in “Indian dermatology online journal” This case report describes a 53-year-old woman with a rare presentation of trichostasis spinulosa on her breast and abdomen, featuring itchy, comedo-like lesions. Dermoscopy revealed diagnostic features that may eliminate the need for a biopsy, highlighting the potential for non-invasive diagnosis in such cases.
19 citations
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July 2018 in “ACS biomaterials science & engineering” This study showed that chemical and mechanical treatments significantly alter the nanoscale surface properties of hair, affecting its roughness, mechanical stiffness, adhesion, and surface potential.
12 citations
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September 2010 in “Clothing and Textiles Research Journal” This preliminary study found that poplar seed hair fibers have promising properties for use as environmentally friendly, lightweight insulation, with similar thermal resistance to wool and polyester despite being slightly less effective than down.
July 2009 in “International Journal of Cosmetic Science” This study found that 53% of Japanese women have straight hair while 47% have varying degrees of curved hair, with distinct structural differences observed in the internal makeup of curved hair fibers.
17 citations
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January 2011 in “Indian journal of dermatology, venereology, and leprology” This paper describes a rare case of keratosis follicularis spinulosa decalvans in a nine-year-old girl, a condition typically more severe in males due to its X-linked inheritance.
7 citations
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July 2025 in “The Journal of Physiology” This study found that human C-tactile afferents respond to hair deflection, suggesting a functionally relevant anatomical relationship to hair follicles similar to that observed in mice.
Hair can't be as strong as Rapunzel's because it's impractical to scale up due to defects.
1 citations
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July 2022 in “Journal of Drug Delivery Science and Technology” This study found that Spironolactone-loaded ethosomal gels provided superior skin permeation and deposition compared to niosomal gels in rabbit skin, suggesting that ethosomal gels could be a promising formulation for further clinical studies on treating androgenic alopecia.
April 2026 in “Colloids and Surfaces B Biointerfaces” In this study, a nanofiber system made from α-lactalbumin and soy protein isolate via a waterborne electrospinning process significantly improved wound healing in a rat model of third-degree burns, enhancing outcomes such as re-epithelialization, collagen deposition, and angiogenesis compared to controls.
June 2026 in “Frontiers in Cell and Developmental Biology” In this study, researchers used single-cell RNA sequencing to map the hair follicle microenvironment in fine-wool sheep, identifying specific cell types and gene expressions that influence wool fiber diameter, with dermal papilla cells playing a significant role in hair follicle development.
January 2000 in “Zhongguo yixue wulixue zazhi” This study observed that human hair keratin showed distinct morphological features depending on the dissolution speed, which could have potential applications in clinical settings for developing self-tendons.
33 citations
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July 2007 in “Skin research and technology” The study found that the break force of human hair significantly depends on hair diameter and strain, but not on age, gender, use of hair dye, or drugs.
8 citations
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July 2014 in “Anais Brasileiros de Dermatologia” This article discusses a case of alopecia areata, androgenetic alopecia, and trichostasis spinulosa, highlighting how dermoscopy can help differentiate black dots from trichostasis spinulosa lesions, but it reports no new clinical results.
3 citations
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October 2024 in “Animals” In this proteomic analysis, the researchers found that transitioning from crimped to straight wool in Tan sheep is linked to significant changes in wool protein expression, revealing distinct patterns of keratins and keratin-associated proteins that could influence wool quality and economic value.
7 citations
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February 1998 in “Polymer journal” This study found that the stability of the coiled-coil structure in human hair keratin is maintained by ion-pairing and hydrophobic interactions, which are disrupted as pH approaches 7.0.
May 2024 in “Scientific reports” This study explored the role of Twist2 in fetal wound healing in embryonic mice, observing that its expression was vital for scarless regeneration and normal hair follicle formation; Twist2 knockdown led to visible scars and defective follicle formation.
March 2024 in “International journal of molecular sciences” In this study on Angora rabbits, researchers identified genetic factors influencing wool fiber diameter by analyzing hair follicle proteins, highlighting keratin family members and other proteins as key contributors to fiber differences between coarse and fine wool.
13 citations
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March 2006 in “International Journal of Cosmetic Science” The study found that a polymer treatment changes the charge on hair surfaces, making bleached hair smoother and less porous.
13 citations
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January 2012 in “International journal of trichology” This case study describes a 14-year-old girl with pili annulati who had fragile hair, which may be due to cavities within the hair shafts as seen in electron microscopic examinations.
December 2009 in “Cancer Research” This study suggests that over-expression of Sp2 may limit stem cell differentiation and contribute to tumorigenic cell growth in mice.
48 citations
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January 2002 in “Journal of Structural Biology” This study reports that trichocyte intermediate filaments from rat vibrissae and human hair follicles may contain a hollow region at their core, suggesting unique structural properties.
1 citations
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January 2017 in “Indian Dermatology Online Journal” This commentary reviews clinical trials on platelet-rich plasma treatments for androgenetic alopecia and emphasizes the need for standardized preparation methods and concentrations; it reports no new clinical results.
3 citations
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August 2010 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This case study describes a child with severe cicatricial alopecia that began at birth and progressed rapidly, making treatment results disappointing.
July 2022 in “Journal of Investigative Dermatology” This study found that Substance P increased mitochondrial activity and biogenesis markers in cultured human scalp hair follicles, suggesting a novel link between stress-related neuropeptide signaling and hair follicle mitochondrial responses.
2 citations
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June 2020 in “International Journal of Research -GRANTHAALAYAH” This manuscript presents a hypothesis linking the intrinsic pulsating bioelectromagnetism of human hair follicles to the etiology of migraine headaches, supported by studies of inherent biomagnetism using optical microscopy techniques.
4 citations
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March 2020 in “Scientific Reports” This study reported that polymeric nanofibers containing minoxidil sulphate showed effective encapsulation and stability, with minimal concentration loss over six months, making them potentially ideal for delivering this unstable drug in a more visually appealing and easier-to-apply form.