Colored Polymeric Nanofiber Loaded with Minoxidil Sulphate for Beauty Coverage and Hair Loss Restoration

    March 2020 in “ Scientific Reports
    Fadilah Sfouq Aleanizy, Abdulrahman A. Almehizia, Hamad M. Alkahtani, Bushra T. AlQuadeib, Esraa K. Eltayeb, Amal Aldarwesh, Hosam G. Abdelhady, Faiyaz Shakeel
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    Studysummary This study reported that polymeric nanofibers containing minoxidil sulphate showed effective encapsulation and stability, with minimal concentration loss over six months, making them potentially ideal for delivering this unstable drug in a more visually appealing and easier-to-apply form. Our plain-language summary of this paper — not a Tressless recommendation.
    In 2020, researchers developed a colored nanofiber loaded with minoxidil sulphate, a common hair loss treatment, using electrospinning. The nanofibers had an average diameter of 273 nm when blank and 511 nm when loaded with minoxidil sulphate. They showed a 47.4% encapsulation efficiency and a 73% yield. The minoxidil sulphate was released from the nanofiber in an initial burst, followed by a slower release pattern. The nanofiber was stable when stored at room temperature and protected from light, losing only 9.6% of its nominal concentration over 6 months. This solid, colored formula provided a simple, non-messy application and could serve as an effective and aesthetically pleasing treatment for hair loss.
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