Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, the researchers found that tyndallization effectively sterilizes aqueous solutions of hyaluronic acid without diminishing their regenerative properties, and these properties remain intact even at low temperatures, supporting potential applications in cryobiology and cryomedicine.

This article discusses the various administration methods and considerations for testosterone replacement therapy, highlighting the importance of individualized therapeutic monitoring and potential adverse effects, but reports no new clinical results.

This case study reports that a 16-year-old girl with hirsutism and menstrual irregularities was diagnosed with a benign steroid cell ovarian tumor, after high testosterone levels indicated a potential androgen-secreting source.

This study found that finasteride reduced sperm count, motility, and levels of reproductive hormones, indicating negative effects on fertility in albino male rats.

In this rat study, finasteride treatment significantly reduced body, testis, epididymis, and prostate weights and affected testicular histology, indicating potential negative impacts on testicular function.

This review suggests that telocytes in male reproductive organs help organize tissue structure and paracrine factors, impacting organ development and pathology, but more research is needed on their molecular pathways.

This study suggests that increased putrescine levels may disrupt normal hair follicle development in transgenic mice, leading to hair loss and altered skin structure, yet these mice appear more resistant to skin tumorigenesis.

This research explored methods to obtain transgenic sheep embryos expressing synthetic spider silk genes in hair follicles using somatic cell nuclear transfer, with successful in-vitro development observed.

Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.

This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.

Finasteride negatively affects fish reproduction and gonadal development.

This study reports that in young male patients with finasteride-associated infertility, semen parameters appear reversible after discontinuing the medication.

This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.

In this study, researchers found that barrier-enhancing formulations significantly reduced the penetration of proteins into hair follicles in porcine skin models, with effectiveness varying by formulation.

In this study, all five serotypes of Ureaplasma were found to be pathogenic in a mouse model of lower genital tract infection, with serotype 4 showing the greatest pathogenicity.

In this case report, a male patient's semen parameters improved after discontinuing a 1-mg dose of finasteride, suggesting that stopping the medication may benefit infertile men with previous sperm production issues.

This study found that finasteride induced infertility and increased endoplasmic reticulum stress in rats, but these effects were mitigated by DA-9401 administration.

This study observed that during male silkmoth development, trichogen cells in olfactory sensilla undergo significant membrane recycling, contributing to sensillum structure formation in a precisely timed series of stages.

This review examines the roles of testosterone, dihydrotestosterone, and estradiol in activating male sexual behavior in laboratory animals and humans, reporting no new clinical results.

In this study, anal beta-papillomavirus infection was found to be highly prevalent among Slovenian MSM, with higher rates observed in HIV-1 positive individuals and those using alkyl nitrates.

Finasteride may cause weak ejaculation and reduced semen volume.

This case report describes two German shepherd dogs with prostatitis that showed favorable responses to treatment with finasteride, phenazopyridine, and enrofloxacin.

This article reviews the effect of aging on male hormone levels and fertility, highlighting the need for more research on the benefits and risks of androgen supplementation in older men.

Finasteride is effective and safe.

In this research, Sertoli cell line model ST38c demonstrated that the androgen receptor regulates hormone pathways through specific coregulators, suggesting roles for SRC-2 and HBO1 in testicular development and androgen responsiveness.

In this case report, goserelin, a GnRH agonist, was effective in managing stuttering priapism and improving erectile function in a patient with sickle cell disease, suggesting potential for last-line treatment.

This review highlights that various commonly prescribed medications for chronic conditions may impact male fertility by affecting hormone secretion, sperm production, ejaculation, erectile function, and libido, although conclusive evidence is limited to specific drug groups.

This study found that Zhuangyao Jianshen pill significantly improved prostate health in testosterone-induced benign prostatic hyperplasia in castrated rats by modulating sex hormones and reducing inflammation and oxidative stress.

This review discusses the potential risks of ejaculatory dysfunction associated with both medical and surgical treatments for lower urinary tract symptoms due to benign prostatic hyperplasia and their implications for male fertility, but it reports no new clinical results.