Prevention of Follicular Penetration: Barrier-Enhancing Formulations Against the Penetration of Pollen Allergens into Hair Follicles
January 2010
in “
Skin pharmacology and physiology
”
Studysummary In this study, researchers found that barrier-enhancing formulations significantly reduced the penetration of proteins into hair follicles in porcine skin models, with effectiveness varying by formulation.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
In a study conducted on porcine skin, researchers investigated the potential of barrier-enhancing emulsions to prevent the penetration of pollen allergens into hair follicles. The skin was pretreated with four different barrier-enhancing emulsions, while one area was left untreated as a control. Following the application of fluorescein-isothiocyanate-labeled grass pollen proteins, fluorescent laser scanning microscopy revealed that the barrier-enhancing formulations significantly reduced the penetration of these exogenous proteins into the hair follicles. The effectiveness varied depending on the specific formulation used. This suggests that such formulations could be a viable strategy for protecting hair follicles from allergen penetration.
