Prevention of Follicular Penetration: Barrier-Enhancing Formulations Against the Penetration of Pollen Allergens into Hair Follicles

    January 2010 in “ Skin pharmacology and physiology ”
    Martina C. Meinke, Alexa Patzelt, Heike Richter, Sabine Schanzer, Wolfram Sterry, Alexander Filbry, K. Bohnsack, Frank Rippke, J Galecka, Regina Fölster‐Holst, Juergen Lademann
    TLDR Special creams can significantly reduce pollen allergens getting into hair follicles.
    In a study conducted on porcine skin, researchers investigated the potential of barrier-enhancing emulsions to prevent the penetration of pollen allergens into hair follicles. The skin was pretreated with four different barrier-enhancing emulsions, while one area was left untreated as a control. Following the application of fluorescein-isothiocyanate-labeled grass pollen proteins, fluorescent laser scanning microscopy revealed that the barrier-enhancing formulations significantly reduced the penetration of these exogenous proteins into the hair follicles. The effectiveness varied depending on the specific formulation used. This suggests that such formulations could be a viable strategy for protecting hair follicles from allergen penetration.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 1000+ results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 6 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
      Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      in Research  862 upvotes 3 months ago
      The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

      community My microneedling journey (no min, fin, etc)

      in Microneedling  210 upvotes 4 months ago
      The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

      community Hair loss 30F - thoughts on red light therapy vs min/fin?

      in Female  6 upvotes 4 months ago
      The conversation discusses hair loss treatments for a 30-year-old female, comparing red light therapy with minoxidil and finasteride. Concerns about hormonal impact and potential pregnancy are raised, with suggestions to consider spironolactone and microneedling, while emphasizing the importance of consulting a dermatologist.

      community New & Improved Hair Growth Stack for Maximum Results

      in Treatment  2 upvotes 3 weeks ago
      A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

    Related Research

    7 / 7 results