research Effect of 1-Mg Dose of Finasteride on Spermatogenesis and Pregnancy
Finasteride 1-mg doesn't harm sperm or pregnancy chances.
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research Bone Density Is Normal in Male Rats Treated with Finasteride
Finasteride doesn't affect bone density in male rats.
research Endocrine Treatment of Transsexual Persons: An Endocrine Society Clinical Practice Guideline
The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
research Stem Cells and the Niche: A Dynamic Duo
Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
research Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men
Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
research Tributyltin Effects on Ocinebrina Aciculata: Imposex Development, Sterilization, Sex Change, and Population Decline
Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Hidradenitis Suppurativa Treated With Finasteride
Finasteride effectively treats hidradenitis suppurativa for most patients.
research Potential Adverse Effects of Long-Term Testosterone Therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male
The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
research A Position Effect on TRPS1 Is Associated with Ambras Syndrome in Humans and the Koala Phenotype in Mice
A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
research Effects of Dermatological Medications on Male Fertility
Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
research Finasteride Use in the Male Infertility Population: Effects on Semen and Hormone Parameters
Finasteride can reduce fertility in some men, but stopping it increases sperm count.
research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
research A Combined Regimen of Cyproterone Acetate and Testosterone Enanthate as a Potentially Highly Effective Male Contraceptive
The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.
research The Impact of SARS-CoV-2 and COVID-19 on Male Reproduction and Men's Health
COVID-19 might affect male fertility, but more research is needed to understand the full impact.
research Evaluation of Sexual Function With an International Index of Erectile Function in Subjects Taking Finasteride for Androgenetic Alopecia
Finasteride for hair loss has minimal impact on sexual function.
research Finasteride-Associated Male Infertility
Finasteride may cause male infertility, stopping it can help.
research Finasteride-Induced Secondary Infertility Associated with Sperm DNA Damage
Finasteride use may cause sperm damage and infertility, stopping it can improve sperm health.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Finasteride-Associated Male Infertility
Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.
research Androgen Receptor Modulators: A Review of Recent Patents and Reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
research Spermatozoa and Chronic Treatment with Finasteride: A TEM and FISH Study
Finasteride may negatively affect male fertility.
research Bone vs. Fat: Embryonic Origin of Progenitors Determines Response to Androgen in Adipocytes and Osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
research Is Polycystic Ovary Syndrome a Sexual Conflict? A Review
The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
research Morphometric-Stereological and Functional Epididymal Alterations and a Decrease in Fertility in Rats Treated with Finasteride and After a 30-Day Post-Treatment Recovery Period
Finasteride causes lasting fertility decrease in rats.
research Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Infertility and Teratogenicity After Paternal Exposure to Systemic Dermatologic Medications: A Systematic Review
Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.