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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Researchers found 15 new genetic links to skin traits in Japanese women.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Natural remedies for hair and scalp issues are still widely used in Palestine.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Rat dermal papilla cells have unique genes crucial for hair growth.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Finasteride helps hair growth but may cause sexual side effects and depression.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Licorice has many traditional health benefits, but more research is needed to fully support these claims.