Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that in mice with premature ovarian insufficiency, miR-21 enhances ovarian function recovery following umbilical cord-derived mesenchymal stem cell transplantation by influencing specific cellular signaling and immune pathways.

This study suggests that while PCOS phenotype does not affect oocyte quality, a combination of hyperandrogenism and chronic anovulation negatively impacts cumulative pregnancy rates in assisted reproduction.

In this study, the researchers found that tyndallization effectively sterilizes aqueous solutions of hyaluronic acid without diminishing their regenerative properties, and these properties remain intact even at low temperatures, supporting potential applications in cryobiology and cryomedicine.

This study found that nicotine may have a therapeutic role in mitigating the exacerbation of infertility conditions connected with alpha-synuclein-related Parkinson’s disease through molecular interactions identified via pathway analysis.

This commentary discusses the feasibility and challenges of uterine transplantation for transgender women, emphasizing anatomical, hormonal, and ethical considerations without reporting new clinical results.

This review highlights therapeutic options for inducing puberty in males and females with delayed puberty, emphasizing the need for larger trials to establish the best approaches.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

This review discusses the role of exosomes in medical aesthetics, focusing on their mechanisms, production, and preservation, but reports no new clinical results and highlights barriers to their widespread application.

This narrative review emphasizes the significant improvements in mental well-being linked to gender-affirming treatments while highlighting the need for ongoing research into hormone therapy's long-term effects and its impact on transgender individuals' reproductive health.

This source provides a comprehensive guideline for the management of transgender individuals in India, highlighting the need for multidisciplinary diagnosis, counseling for gender-affirming hormone therapy, and the importance of addressing social stigma, legal issues, and medical training to improve healthcare access for this population.

This review discusses the potential impact of COVID-19 on the male reproductive system and highlights unanswered questions regarding its mechanisms and implications for men's health and fertility, reporting no new clinical results.

This review examines sulforaphane's interactions with hormone-mediated health conditions, focusing on gender-specific health issues, but reports no new original research findings.

This review discusses strategies for maintaining access to gender-affirming care for gender diverse youth during the COVID-19 pandemic and reports no new clinical results.

This article reviews congenital adrenal hyperplasia, a group of rare genetic disorders affecting steroid synthesis, and highlights the need for specific therapy and ongoing monitoring, but reports no new clinical findings.

This review outlines recent advances in stem cell and tissue engineering technologies in regenerative medicine and wildlife conservation, reporting no new clinical results.

This study investigated nanocomposite scaffolds made from alginate, chitosan, and graphene oxide to promote the proliferation of spermatogonial stem cells, finding the ALGCS/GO30 scaffold to be particularly effective due to increased proliferation markers and PLZF protein expression compared to controls.

This review outlines the design and engineering of multifunctional hydrogels, emphasizing their evolving biomedical applications, notably in controlled drug delivery, tissue support, and disease management, and discusses their potential for clinical translation.

This systematic review reported positive outcomes with gender-affirming hormone therapy in Canada and emphasized the urgent need for standardized outcome measurement tools to enhance evidence-based practices.

This study found that zinc is primarily located in the tails of mature rat sperm, associated with -S-S-bonded structures, and suggests a possible similarity in zinc interactions between sperm keratin and hair proteins.

This case report suggests that discontinuing low-dose finasteride in a 48-year-old man led to a significant reduction in sperm DNA fragmentation index, indicating a possible link between finasteride and sperm DNA damage.

This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.

This review discusses the risk factors and implications of sperm aneuploidy in males, and it reports no new clinical results; the authors highlight the importance of personalized assessment in assisted reproduction.

This study found that Origanum vulgare extract improved testicular structure and function in mice against finasteride-induced damage by enhancing antioxidant defense and modulating gene expression related to apoptosis.

This study found that finasteride may affect Ca 2+ signalling in human sperm by interacting with the PGE 1 -binding site, but its impact on fertilization requires further investigation.

In this study, high doses of Lepidium sativum seeds extract were reported to cause toxicity and tissue damage in animals, suggesting the need for careful use under medical supervision.

In this study, male patients treated with 150 mCi of radioactive iodine showed no negative impact on fertility, but long-term studies with larger groups are needed to further assess hormonal effects and sperm health after this treatment.

This study found that a mild intramuscular dose of BOTOX increased spermatogenesis and improved sperm quality in ageing mice, suggesting potential benefits for managing male infertility.

This review reports an increasing trend in sperm DNA fragmentation research over the past 20 years, with a focus on lifestyle, asthenozoospermia, and varicocele, and highlights the TUNEL technique as widely used.

This analysis of seven studies explored the impact of finasteride (1mg/day for androgenic alopecia) on sperm concentration, finding that in most studies, sperm concentration increased after stopping treatment, but the largest study showed no change during or after treatment.

This study in Tehran found that, after adjusting for confounders, women with PCOS had no different risk of non-pregnancy after assisted reproductive treatment compared to women without PCOS.