TLDR Women with PCOS have a similar chance of getting pregnant using assisted reproductive treatment as those without PCOS.
In a historical cohort study at the Royan Institute in Tehran, Iran, involving 996 infertile women, researchers investigated the impact of polycystic ovary syndrome (PCOS) on the success of assisted reproductive treatment (ART) using a modified Poisson Regression model. Initially, unadjusted analysis showed a lower risk of ART failure in women with PCOS, but after adjusting for confounders like age, treatment protocol, and number of embryos transferred, the difference in non-pregnancy risk between women with and without PCOS was not significant. The study concluded that PCOS does not significantly affect the risk of non-pregnancy in ART patients, and that other factors are likely influential in conception outcomes for PCOS patients. The study also highlighted the need for future research to include long-term follow-up on pregnancy complications and outcomes in newborns from IVF/ICSI, especially in women with PCOS.
951 citations,
December 2013 in “Clinical epidemiology” PCOS is a common hormonal disorder in women that can be managed with lifestyle changes and various medications.
991 citations,
January 2011 in “Nature Reviews Endocrinology” The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.
215 citations,
January 2011 in “Reproductive Biology and Endocrinology” About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.
989 citations,
August 2007 in “The Lancet” PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.
September 2023 in “Diagnostics” Low vitamin D levels may affect ovulation and progesterone in infertile women.
July 2015 in “Cambridge University Press eBooks” The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.
5 citations,
October 2012 in “Journal of Midwifery & Women's Health” Healthcare providers should start with simple fertility tests and treatments before referring patients to specialists.
53 citations,
February 2022 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.
36 citations,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
