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Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Red clover extract improved hair, skin, mood, sleep, and tiredness in postmenopausal women.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Finasteride negatively affects fish reproduction and gonadal development.

The review suggests renaming two herbs to avoid confusion and recommends more research for safe use.

Adding yeast extract and methyl jasmonate to Eclipta alba cell cultures increased the production of the compound wedelolactone.

Choline and biotin are important for liver health and preventing certain deficiencies in animals, and more research is needed to understand their benefits in humans.

Mange in rabbits is a serious disease that can spread to humans and is treated with medications and supportive care.

Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.

Some alternative therapies for vitiligo show promise but need more research.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Some drugs have gained approval for new uses, while others like tricyclic antidepressants and aspirin show promise but aren't yet approved for these uses.

Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

Women with PCOS face many health risks, but exercise, a healthy diet, and weight management can help.

Bee pollen, green tea, essential oils, and various plant extracts improve skin and hair health.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.