Medical Care for Children and Adolescents with Gender Dysphoria and Gender Inconsistency in Light of Current Recommendations: How to Implement the 'Primum Non Nocere' Principle?

    September 2023 in “ Fides et Ratio
    Joanna Smyczyñska
    Image of study
    TLDR The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.
    The document discusses the increasing trend of using puberty blockers and sex steroids in children and adolescents with gender dysphoria or gender inconsistency to inhibit the development of their natal sexual characteristics and mimic those of their identified gender. It highlights the lack of evidence regarding the effectiveness and safety of these gender-affirming therapies, as well as the potential influence of peer groups and media on the rise of gender identity disorders. The paper also notes the serious long-term consequence of infertility associated with these treatments and mentions that some countries, like Sweden, have tightened legal regulations in response. The bioethical and legal aspects of these issues are acknowledged as requiring further attention and study.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 452 results

      community 6 Months topical 5% minoxidil twice a day.

      in Progress Pictures  147 upvotes 1 week ago
      The user has been using topical 5% minoxidil for six months with minimal results and is worried about greasy hair and potential side effects of adding finasteride. Others suggest combining minoxidil with finasteride for better results, while discussing potential side effects like erectile dysfunction.

      community 200 days on dut + min, what do you think?

      in Is this regrowth?  599 upvotes 1 month ago
      The user reports significant hair regrowth after 200 days using dutasteride and minoxidil, attributing changes to hair dye. Others doubt the authenticity and discuss treatment effectiveness and side effects.

      community Hair loss research is a money grab

      in Chat  217 upvotes 1 week ago
      Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  169 upvotes 1 year ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

    Similar Research

    5 / 1000+ results