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A man got severe skin irritation after using marking nut sap for hair loss.

In this study, fMRI results suggested that mechanical stimulation evoked a stronger prickle sensation comprising both pain and itch on hairy skin compared to glabrous skin.

This case study describes a unique instance of unilateral steroid-induced rosacea-like dermatitis likely due to long-term localized use of topical corticosteroids, emphasizing the need for careful application and thorough histopathological analysis.

Keloid fibroblasts cause itch and pain by releasing more histamine.

This case study suggests that thermography could objectively assess pain severity in herpes zoster patients by correlating thermal images with reported pain intensity.

In this study, the novel isoprenylcysteine analog SIG-1451 was shown to inhibit pro-inflammatory cytokine release in various cell-based assays relevant to allergic dermatitis, acting on targets such as IL-4 and IL-6 with potential anti-inflammatory benefits.

This study found that in participants with notalgia paresthetica, 8 weeks of treatment with difelikefalin significantly improved itch intensity and increased the rate of strict complete response compared to placebo, starting as early as week 3.

This study found that osthole, a coumarin derivative, demonstrated significantly higher skin accumulation and potential skin irritation compared to coumarin, which showed negligible alterations in protein biomarkers.

This study suggests that fatigue, joint pain, and light sensitivity are significant impacts for systemic lupus erythematosus patients, highlighting areas of unmet need in current treatment options.

In this study, using EMLA cream did not adequately control pain during and after scalp PRP injections for androgenetic alopecia, with anxiety and younger age linked to higher pain levels.

In this study, a newly developed nanoparticle-loaded hydrogel wound dressing demonstrated significant antibacterial, antioxidant, anti-inflammatory, and proangiogenic activities, effectively reducing pain and promoting healing in a murine burn wound model while preventing infection by *Staphylococcus aureus*.

This report observed that repeated stellate ganglion blocks over six years were associated with improved skin elasticity, increased water content, and more hair follicles on the treated side of a patient's face.

This study found that patients experienced less pain when using a 1-mL syringe compared to a 3-mL syringe, despite both having the same needle size.

This source reports that while creatine supplementation is popular for improving muscle mass and performance, questions about its efficacy and safety persist. An expert team is reviewing literature to address concerns like water retention, renal effects, and its benefits across different populations and uses.

This review discusses management strategies for sexual side effects of aromatase inhibitors in postmenopausal breast cancer patients and reports no original clinical findings.

This review collected findings on the various cosmetic and therapeutic properties of tea extracts, highlighting their antioxidant, anti-inflammatory, and photoprotective effects among other benefits for skin and hair care.

This study found that hidradenitis suppurativa significantly impaired quality of life in German patients, with severity linked to skin and certain extra-cutaneous changes, but not reduced by surgical or conventional medicamentous treatments.

This case report described a probable case of acute liver injury associated with high-dose S. repens, highlighting the safety concerns of self-medicating with herbal supplements like saw palmetto.

This review examined how COVID-19 infection and vaccination might affect sexual activity, sex hormones, and menstrual cycles in men and women, and found no evidence of COVID-19 transmission via semen.

This review highlights that platelet-rich plasma and adipose-derived stem cell therapy may offer safe and promising improvements for managing symptoms of genital lichen sclerosus, with a potential synergistic benefit when combined.

This review found that the DLQI is widely used as a benchmark in the development and validation of dermatology quality-of-life measures.

This study reports that negative pressure wound therapy combined with PRP may effectively accelerate wound healing and reduce mortality in diabetic foot ulcers, with albumin and age identified as independent predictors of mortality risk.

Fenugreek leaf extracts significantly promoted hair growth in mice with alopecia.

This review discusses the complex interplay of genetic and environmental factors in Type 1 Diabetes Mellitus and its frequent association with other autoimmune conditions, focusing on personalized medicine to potentially improve patient care.

This case report details the dermoscopic features of oral lichen planus in a young adult male, using mucoscopy to reveal a tri-colored pattern with unique structures and vascular patterns.

The authors concluded that while PRP is a promising and well-tolerated treatment for early to moderate knee osteoarthritis, standardizing preparation protocols, patient selection, and outcome reporting is crucial to enhance comparability and inform clinical practice.

This study investigated the effects of the 60% alcohol extract from Alnus sibirica and its active compound, oregonin, on hair health, observing anti-oxidative and anti-apoptotic benefits in human hair dermal papilla cells exposed to oxidative stress, suggesting potential as natural materials for hair loss prevention.

This review describes adipose tissue-derived therapies as promising for osteoarthritis, with potential to repair cartilage, reduce inflammation, and enhance joint function, highlighting advancements and their potential future applications.

This study suggests that guava leaf extract may inhibit hair loss by downregulating genes involved in androgen synthesis, potentially offering a natural alternative for treating androgenetic alopecia.

This review notes that while ATX-101 showed a favorable safety profile for reducing submental fat in clinical trials, serious adverse events related to procedures have been reported in real-world use, prompting recommendations for improved management and prevention strategies.