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Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

DNA methylation controls lncRNA2919, which negatively affects hair growth.

WWP2 is crucial for tooth development in mice.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Cholesterol-modified siRNAs targeting certain genes increased hair growth in mice.

Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Both mouse and rat models are effective for testing alopecia areata treatments.

Surface-modified nanostructured lipid carriers can improve hair growth treatments.

Autophagy is important for human hair growth and health.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

GLI2 increases follistatin production in human skin cells.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

The research identifies genes linked to wool quality in sheep and provides insights to improve wool production.