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Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Melatonin treatment helps improve skin health in postmenopausal rats.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.

CD4+ skin cells may be precursors to basal cell carcinoma.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Aging causes skin stem cells to work less effectively.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.

TCDD disrupts skin stem cells, causing skin issues like chloracne.

Dermal EZH2 controls skin cell development and hair growth in mice.

Dermal EZH2 controls skin cell growth and differentiation in mice.