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Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Hair growth environment recreated with challenges; stem cells make successful skin organoids.

Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.

Soy protein with isoflavones reduces wrinkles and improves skin hydration in postmenopausal women.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

The paper concludes that elderly in India face unique skin challenges and need better dermatological care and awareness.

Using gelatin sponges for deep skin wounds helps bone marrow cells repair tissue without scarring.

Epigenetic factors play a crucial role in skin health and disease.

Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.

Thyroid problems are linked to various skin issues, and checking thyroid health is important for people with certain skin conditions.

A man had rare skin tumors with bone formation and cholesterol deposits.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

The new method using gene-modified stem cells and a 3D printed scaffold improved skin repair in mice.

Choosing the right method to separate skin layers is key for good skin cell research.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

New scaffold materials help heal severe skin wounds and improve skin regeneration.

PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

PRP helps with skin, hair, and wound treatments but needs more research for standard use.

Vegan collagen builder improves hair growth, skin smoothness, and reduces wrinkles and pain.

Plasma gel and PRP treatments improve skin and hair with minimal side effects.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

Hormone replacement therapy may improve hair growth in the frontal hairline of postmenopausal women with hair loss.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.