77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
75 citations,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
67 citations,
January 2022 in “Theranostics” Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
47 citations,
March 2022 in “Frontiers in cellular and infection microbiology” Changes in skin microbes play a role in some skin diseases and could lead to new treatments.
38 citations,
June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
17 citations,
August 2019 in “Frontiers in Immunology” Non-invasive methods show promise for diagnosing skin diseases like psoriasis and lupus but need more research for regular use.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
13 citations,
April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
9 citations,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
4 citations,
November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
4 citations,
July 2013 in “Journal of Dermatological Science” Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.
1 citations,
January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
1 citations,
April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
September 2014 in “Aktuelle Dermatologie” The symposium concluded that environmental factors significantly contribute to skin aging.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
192 citations,
March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
98 citations,
December 2008 in “Journal of Investigative Dermatology” Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
21 citations,
November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
144 citations,
November 2020 in “Frontiers in immunology” Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
66 citations,
May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
32 citations,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
51 citations,
December 2017 in “Skin Appendage Disorders” Stress may trigger hair loss by affecting immune protection in hair follicles.
15 citations,
October 2012 in “InTech eBooks” Niosomes are a promising and effective way to deliver drugs through the skin.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
50 citations,
September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
3 citations,
July 2017 in “Elsevier eBooks” Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.